Structure of PDB 3fv3 Chain G Binding Site BS01

Receptor Information
>3fv3 Chain G (length=339) Species: 5480 (Candida parapsilosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSISLSLINEGPSYASKVSVGSNKQQQTVIIDTGSSDFWVVDSNAQCGKG
VDCKSSGTFTPSSSSSYKNLGAAFTIRYGDGSTSQGTWGKDTVTINGVSI
TGQQIADVTQTSVDQGILGIGYTSNEAVYDTSGRQTTPNYDNVPVTLKKQ
GKIRTNAYSLYLNSPSAETGTIIFGGVDNAKYSGKLVAEQVTSSQALTIS
LASVNLKGSSFSFGDGALLDSGTTLTYFPSDFAAQLADKAGARLVQVARD
QYLYFIDCNTDTSGTTVFNFGNGAKITVPNTEYVYQNGDGTCLWGIQPSD
DTILGDNFLRHAYLLYNLDANTISIAQVKYTTDSSISAV
Ligand information
>3fv3 Chain O (length=6) Species: 285516 (Streptomyces argenteolus subsp. toyonakensis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
VVVLAL
Receptor-Ligand Complex Structure
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PDB3fv3 The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A
Resolution1.85 Å
Binding residue
(original residue number in PDB)		D32 G34 Y78 G79 D80 D220 G222 T223 T224 Y227 Y285 D301
Binding residue
(residue number reindexed from 1)		D32 G34 Y78 G79 D80 D220 G222 T223 T224 Y227 Y285 D301
Enzymatic activity
Catalytic site (original residue number in PDB) D32 S35 D37 W39 Y78 D220 T223
Catalytic site (residue number reindexed from 1) D32 S35 D37 W39 Y78 D220 T223
Enzyme Commision number 3.4.23.24: candidapepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Biological Process
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Cellular Component
External links
PDB RCSB:3fv3, PDBe:3fv3, PDBj:3fv3
PDBsum3fv3
PubMed19401235
UniProtP32951|CARP1_CANPA Candidapepsin-1 (Gene Name=SAPP1)

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