Structure of PDB 2i5y Chain G Binding Site BS01

Receptor Information
>2i5y Chain G (length=302) Species: 12721 (Human immunodeficiency virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEVKLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVGAGS
CNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTV
QCTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTNNAKTIIVQLNESVVIN
CTGAGHCNLSKTQWENTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTH
SFNCGGEFFYCNSTQLFTWNDRNITLPCRIKQIINMWQEVGKAMYAPPIR
GQIRCSSNITGLLLTRDGGKDTNGTEIFRPGGGDMRDNWRSELYKYKVVK
IE
Ligand information
>2i5y Chain M (length=27) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CNLHFCQLRCKSLGLLGRCAPTFCACV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2i5y Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
V255 S365 G366 G367 D368 E370 I371 N425 M426 W427 E429 V430 G473
Binding residue
(residue number reindexed from 1)
V110 S191 G192 G193 D194 E196 I197 N235 M236 W237 E239 V240 G283
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:2i5y, PDBe:2i5y, PDBj:2i5y
PDBsum2i5y
PubMed18619974
UniProtP35961|ENV_HV1Y2 Envelope glycoprotein gp160 (Gene Name=env)

[Back to BioLiP]