Structure of PDB 2bcg Chain G Binding Site BS01

Receptor Information
>2bcg Chain G (length=442) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TIDTDYDVIVLGTGITECILSGLLSVDGKKVLHIDKQDHYGGEAASVTLS
QLYEKFKQNPISKEERESKFGKDRDWNVDLIPKFLMANGELTNILIHTDV
TRYVDFKQVSGSYVFKQGKIYKVPANEIEAISSPLMGIFEKRRMKKFLEW
ISSYKEDDLSTHQGLDLDKNTMDEVYYKFGLGNSTKEFIGHAMALWTNDD
YLQQPARPSFERILLYCQSVARYGKSPYLYPMYGLGELPQGFARLSAIYG
GTYMLDTPIDEVLYKKDTGKFEGVKTKLGTFKAPLVIADPTYFPEKCKST
GQRVIRAICILNHPVPNTSNADSLQIIIPQSQLGRKSDIYVAIVSDAHNV
CSKGHYLAIISTIIETDKPHIELEPAFKLLGPIEEKFMGIAELFEPREDG
SKDNIYLSRSYDASSHFESMTDDVKDIYFRVTGHPLVLKQRQ
Ligand information
Ligand IDGER
InChIInChI=1S/C20H34/c1-7-18(4)12-9-14-20(6)16-10-15-19(5)13-8-11-17(2)3/h7,11,14-15H,8-10,12-13,16H2,1-6H3/b18-7+,19-15+,20-14+
InChIKeyHSOYJGBJQAKCNA-CAIKYXSQSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04C(=C/CCC(=C/C)/C)(\CC/C=C(/CC/C=C(\C)C)C)C
OpenEye OEToolkits 1.5.0C\C=C(/C)\CC\C=C(/C)\CC\C=C(/C)\CCC=C(C)C
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C
CACTVS 3.341C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C
FormulaC20 H34
NameGERAN-8-YL GERAN
ChEMBL
DrugBank
ZINCZINC000014880577
PDB chain2bcg Chain G Residue 4000 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2bcg Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling
Resolution1.48 Å
Binding residue
(original residue number in PDB)		P128 F192
Binding residue
(residue number reindexed from 1)		P124 F188
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005092 GDP-dissociation inhibitor activity
GO:0005093 Rab GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2bcg, PDBe:2bcg, PDBj:2bcg
PDBsum2bcg
PubMed16395334
UniProtP39958|GDI1_YEAST Rab GDP-dissociation inhibitor (Gene Name=GDI1)

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