Structure of PDB 1yym Chain G Binding Site BS01

Receptor Information
>1yym Chain G (length=301) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVKLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVGAGSC
NTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQ
CTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTNNAKTIIVQLNESVVINC
TGAGHCNLSKTQWENTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTHS
FNCGGEFFYCNSTQLFTWNDRNITLPCRIKQIINMWQEVGKAMYAPPIRG
QIRCSSNITGLLLTRDGGKDTNGTEIFRPGGGDMRDNWRSELYKYKVVKI
E
Ligand information
>1yym Chain M (length=27) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CNLHFCQLRCKSLGLLGKCAGSFCACV
Receptor-Ligand Complex Structure
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PDB1yym Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
G366 G367 D368 E370 I371 N425 M426 W427 V430 G473 D474
Binding residue
(residue number reindexed from 1)
G191 G192 D193 E195 I196 N234 M235 W236 V239 G282 D283
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:1yym, PDBe:1yym, PDBj:1yym
PDBsum1yym
PubMed15893666
UniProtP35961|ENV_HV1Y2 Envelope glycoprotein gp160 (Gene Name=env)

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