Structure of PDB 1rgi Chain G Binding Site BS01

Receptor Information
>1rgi Chain G (length=346) Species: 9796 (Equus caballus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQ
LRNGILQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGF
ESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLLQVKGRRVVRATE
VPVSWESFNNGDCFILDLGNNIYQWCGSKSNRFERLKATQVSKGIRDNER
SGRAQVSVFEEGAEPEAMLQVLGPKPTLPEATEDTVKEDAANRKLAKLYK
VSNGAGPMVVSLVADENPFAQGALRSEDCFILDHGKDGKIFVWKGKQANM
EERKAALKTASDFISKMDYPKQTQVSVLPEGGETPLFRQFFKNWRD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1rgi Chain G Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1rgi Structure of the N-terminal half of gelsolin bound to actin: roles in severing, apoptosis and FAF
Resolution3.0 Å
Binding residue
(original residue number in PDB)		G65 D66 E97 V145
Binding residue
(residue number reindexed from 1)		G40 D41 E72 V120
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0051015 actin filament binding

View graph for
Molecular Function
External links
PDB RCSB:1rgi, PDBe:1rgi, PDBj:1rgi
PDBsum1rgi
PubMed15215896
UniProtQ28372|GELS_HORSE Gelsolin (Gene Name=GSN)

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