Structure of PDB 1p8z Chain G Binding Site BS01

Receptor Information
>1p8z Chain G (length=131) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQ
LRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGF
ESATFLGYFKSGLKYKKGGVASGFKHVVPNE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1p8z Chain G Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1p8z From the First to the second domain of gelsolin: A common path on the surface of actin?
Resolution2.6 Å
Binding residue
(original residue number in PDB)		G65 D66 E97 V145
Binding residue
(residue number reindexed from 1)		G40 D41 E72 V120
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0051015 actin filament binding

View graph for
Molecular Function
External links
PDB RCSB:1p8z, PDBe:1p8z, PDBj:1p8z
PDBsum1p8z
PubMed14527665
UniProtP06396|GELS_HUMAN Gelsolin (Gene Name=GSN)

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