Structure of PDB 1gxc Chain G Binding Site BS01
Receptor Information
>1gxc Chain G (length=116) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
PWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSK
KHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIAL
SLSRNKVFVFFDLTVD
Ligand information
>1gxc Chain H (length=8) Species:
32630
(synthetic construct) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
HFDTYLIR
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
1gxc
Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
R117 R137 T138 Y139 S140 K141 N166
Binding residue
(residue number reindexed from 1)
R26 R46 T47 Y48 S49 K50 N75
Enzymatic activity
Enzyme Commision number
2.7.11.1
: non-specific serine/threonine protein kinase.
External links
PDB
RCSB:1gxc
,
PDBe:1gxc
,
PDBj:1gxc
PDBsum
1gxc
PubMed
12049740
UniProt
O96017
|CHK2_HUMAN Serine/threonine-protein kinase Chk2 (Gene Name=CHEK2)
[
Back to BioLiP
]
