Structure of PDB 1g0u Chain G Binding Site BS01

Receptor Information

>1g0u Chain G (length=240) Species: 4932 (Saccharomyces cerevisiae)

DRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDK
LLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDM
PCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPAGY
YVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMID
ALGTEFSKNDLEVGVATKDKFFTLSAENIEERLVAIAEQD

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 1g0u Chain G Residue 9001

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1g0u A gated channel into the proteasome core particle.
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): T13 Y123 R126 A127 M129
• Binding residue (residue number reindexed from 1): T5 Y116 R119 A120 M122
• Annotation score: 4

Enzymatic activity

• Enzyme Commision number: 3.4.99.46: Transferred entry: 3.4.25.1.

Gene Ontology

Molecular Function

• GO:0003674 molecular_function
• GO:0005515 protein binding

Biological Process

• GO:0006511 ubiquitin-dependent protein catabolic process
• GO:0010499 proteasomal ubiquitin-independent protein catabolic process
• GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
• GO:0051603 proteolysis involved in protein catabolic process

Cellular Component

• GO:0000502 proteasome complex
• GO:0005634 nucleus
• GO:0005737 cytoplasm
• GO:0005739 mitochondrion
• GO:0005839 proteasome core complex
• GO:0019773 proteasome core complex, alpha-subunit complex

External links

• PDB: RCSB:1g0u, PDBe:1g0u, PDBj:1g0u
• PDBsum: 1g0u
• PubMed: 11062564
• UniProt: P21243|PSA1_YEAST Proteasome subunit alpha type-1 (Gene Name=SCL1)