Structure of PDB 1ca0 Chain G Binding Site BS01

Receptor Information
>1ca0 Chain G (length=131) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDV
VVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFS
QTVSAVCLPSASDDFAAGTTCVTTGWGLTRY
Ligand information
Receptor-Ligand Complex Structure
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PDB1ca0 Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		V23 S26 W27 P28 W29 Q116 A120 V121 C122 V137
Binding residue
(residue number reindexed from 1)		V8 S11 W12 P13 W14 Q101 A105 V106 C107 V122
Enzymatic activity
Catalytic site (original residue number in PDB) H57 D102
Catalytic site (residue number reindexed from 1) H42 D87
Enzyme Commision number 3.4.21.1: chymotrypsin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1ca0, PDBe:1ca0, PDBj:1ca0
PDBsum1ca0
PubMed9300481
UniProtP00766|CTRA_BOVIN Chymotrypsinogen A

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