Structure of PDB 1aqd Chain G Binding Site BS01
Receptor Information
>1aqd Chain G (length=177) Species:
9606
(Homo sapiens) [
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EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWE
Ligand information
>1aqd Chain I (length=14) Species:
9606
(Homo sapiens) [
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GSDWRFLRGYHQYA
Receptor-Ligand Complex Structure
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PDB
1aqd
The class II MHC protein HLA-DR1 in complex with an endogenous peptide: implications for the structural basis of the specificity of peptide binding.
Resolution
2.45 Å
Binding residue
(original residue number in PDB)
Q9 F24 I31 F32 A52 S53 F54 G58 A61 N62 V65 N69 I72 M73 R76
Binding residue
(residue number reindexed from 1)
Q7 F22 I29 F30 A50 S51 F52 G56 A59 N60 V63 N67 I70 M71 R74
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:1aqd
,
PDBe:1aqd
,
PDBj:1aqd
PDBsum
1aqd
PubMed
9351812
UniProt
P01903
|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)
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