Structure of PDB 7pub Chain Fg Binding Site BS01

Receptor Information
>7pub Chain Fg (length=513) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRALVFSGQGAHRRGMATEYLRIPAVACLWERMKGSMEQKYGISLQDIIT
ENPTRLYVYNDAYDVAAICERSCQDGGSVVESTPKQKLISHPQGVLSLTS
LTQPCMLAAHMVSLEYLKETRGYSVESSEVIAGHSLGEFSALCALGVLSP
EVAIDLVYRRGALMEDAVKHSSQSNEGHLMFACNPQRAKLCVEDPDLAVD
QLHIFVELIARNLSTTASFIEVVNYNISYEQYVVVGDPIALSALGKCLDP
QFRATSCGSSATLDNIVRTAVSSVLQDKQEGITMNPNTGPAPDFVTSCAR
KYGIRSTFRRFLRGPDDGYTPSLEELTHLTLQEDGRSGLKKKSWFIPLPL
SIPFHSSMLRRAMDLFLPVVRDALPDEETMRSFFCIPVWLTNLTGTAFRP
FDVDFQRDALDAMQSMNVGEIRHNGRYHTNLVELAFKNGMDTSSVRDMCA
AVLAAQLAHPVQWIDVMDSAVFQHGVREAHEISPVRTVADMFKRTVFALD
IVTRCLPSEERFL
Ligand information
>7pub Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaagugcug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
agguauaugcaaauauaaaauuauaguaauuauaaauuauauuauauuau
auuuauucauauaauuaauaggauaauauuuguaguuuuugauaccauga
uaaggauuauaaauugaaaguguuaauaucauaaucaaaauuuauuauuu
auauuaaauauguauguguagauaaaauaagaaauuaaaaagguauuguu
gcccaccaauuuuuauaauaaaaauaacgugcaguaauuaauauauuuau
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....................<<<.......<<<<<<............<.
..>..........................................<....
.<<...<<<.......>>>..>>........>........<<....>>..
..................................................
.................<<<.....<<<<<.....<<....>>.......
>>>>>>>>....>>.>>>>...............................
..................................................
..............................>>>....<............
.<<<<<............................................
..................................................
.....................>>>>>..................>.....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
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PDB7pub Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		K306 Y307 R310
Binding residue
(residue number reindexed from 1)		K301 Y302 R305
Enzymatic activity
Enzyme Commision number 2.3.1.39: [acyl-carrier-protein] S-malonyltransferase.
Gene Ontology
Molecular Function
GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0020023 kinetoplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7pub, PDBe:7pub, PDBj:7pub
PDBsum7pub
PubMed35042777
UniProtQ38DK4

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