Structure of PDB 7tgh Chain FX Binding Site BS01

Receptor Information
>7tgh Chain FX (length=146) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHHHAGDQADRVADKIIWINIQNRIGQFERISAFEGESLLEALQRNKVAG
IVATCEGGEDINTMLEKPIDPVTYGPFCSSCQVVVSNPWRNKMGNLHYLE
ERNLVRSSYPTTENSRLACCILVEKWMNEMIISIPQNPNSVYEDNM
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7tgh Chain FX Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7tgh Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		A79 C81 C104 S105 C107 C145
Binding residue
(residue number reindexed from 1)		A53 C55 C78 S79 C81 C119
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0051536 iron-sulfur cluster binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0140647 P450-containing electron transport chain

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7tgh, PDBe:7tgh, PDBj:7tgh
PDBsum7tgh
PubMed35357889
UniProtQ22W11

[Back to BioLiP]