Structure of PDB 8gym Chain FS Binding Site BS01

Receptor Information
>8gym Chain FS (length=188) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSAILKRAAKYKRVSSILCEGEAHLRDPFTPPPVILKPPAPRKDKKPDDI
TDFPAQKLIPLPESIPYQEGKYRPASIPMVAGFFPYNCYLQQGKVYSWCS
CGISQSGPWCDGLCNSVVTRCRPVVFNVSQSGYYKICNCKFSANAPFCNN
THRKMVRYHHQTHRGFYEIWGAALFVLGWVYMGFNYYT
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8gym Chain FS Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8gym Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Resolution2.96 Å
Binding residue
(original residue number in PDB)		C99 S100 C101 S104 C110 L113 C114 P123
Binding residue
(residue number reindexed from 1)		C99 S100 C101 S104 C110 L113 C114 P123
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0106034 protein maturation by [2Fe-2S] cluster transfer
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8gym, PDBe:8gym, PDBj:8gym
PDBsum8gym
PubMed37248254
UniProtI7M8P0

[Back to BioLiP]