Structure of PDB 7w5z Chain FS Binding Site BS01

Receptor Information
>7w5z Chain FS (length=188) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSAILKRAAKYKRVSSILCEGEAHLRDPFTPPPVILKPPAPRKDKKPDDI
TDFPAQKLIPLPESIPYQEGKYRPASIPMVAGFFPYNCYLQQGKVYSWCS
CGISQSGPWCDGLCNSVVTRCRPVVFNVSQSGYYKICNCKFSANAPFCNN
THRKMVRYHHQTHRGFYEIWGAALFVLGWVYMGFNYYT
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7w5z Chain FS Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7w5z Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Resolution3.02 Å
Binding residue
(original residue number in PDB)		C99 S100 C101 C110 C114 P123
Binding residue
(residue number reindexed from 1)		C99 S100 C101 C110 C114 P123
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0106034 protein maturation by [2Fe-2S] cluster transfer
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7w5z, PDBe:7w5z, PDBj:7w5z
PDBsum7w5z
PubMed35357889
UniProtI7M8P0

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