Structure of PDB 8qfy Chain FFF Binding Site BS01
Receptor Information
>8qfy Chain FFF (length=267) Species:
9606
(Homo sapiens) [
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GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQTELVETRPAGDGTFQKWAAVVVPSGEEQRYTC
HVQHEGLPEPVTLRWKP
Ligand information
>8qfy Chain HHH (length=9) Species:
1773
(Mycobacterium tuberculosis) [
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RLPAKAPLL
Receptor-Ligand Complex Structure
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PDB
8qfy
An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis.
Resolution
2.33 Å
Binding residue
(original residue number in PDB)
Y7 M45 R62 E63 S66 A67 I73 N77 T80 Y84 W97 H99 F116 S143 K146 E152 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 M45 R62 E63 S66 A67 I73 N77 T80 Y84 W97 H99 F116 S143 K146 E152 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8qfy
,
PDBe:8qfy
,
PDBj:8qfy
PDBsum
8qfy
PubMed
38691588
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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