Structure of PDB 6woo Chain FF Binding Site BS01

Receptor Information
>6woo Chain FF (length=201) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FTPVVLATPIPEEVQQAQTEIKLFNKWSFEEVEVKDASLVDYVQVRQPIF
VAHTAGRYANKRFRKAQCPIIERLTNSLMMNGRNNGKKLKAVRIIKHTLD
IINVLTDQNPIQVVVDAITNTGPREDTTRVARRQAVDVSPLRRVNQAIAL
LTIGAREAAFRNIKTIAETLAEELINAAKGSSTSYAIKKKDELERVAKSN
R
Ligand information
>6woo Chain 2 (length=1780) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aucugguugauccugccaguagucauaugcuugucucaaagauuaagcca
ugcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcucau
uaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguug
gccggucgauuuuccaacggggccuuuccuucuggcuaaccuugaguccu
uguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguuc
aaagcaggcguauugcucgaauauauuagcauggaauaauagaauaggac
guuugguucuauuuuguugguuucuaggaccaucguaaugauuaauaggg
acggucgggggcaucaguauucaauugucagaggugaaauucuuggauuu
auugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaau
caagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucuu
aaccauaaacuaugccgacuagggaucgggugguguuuuuuuaaugaccc
acucggcaccuuacgagaaaucaaagucuuuggguucuggggggaguaug
gucgcaaggcugaaacuuaaaggaauugacggaagggcaccaccaggagu
ggagccugcggcuuaauuugacucaacacggggaaacucaccagguccag
acacaauaaggauugacagauugagagcucuuucuugauuuugugggugg
uggugcauggccguucuuaguugguggagugauuugucugcuuaauugcg
auaacgaacgagaccuuaaccuacuaaauaguggugcuagcauuugcugg
uuauccacuucuuagagggacuaucgguuucaagccgauggaaguuugag
gcaauaacaggucugugaugcccuuagacguucugggccgcacgcgcgcu
acacugacggagccagcgagucuaaccuuggccgagaggucuugguaauc
uugugaaacuccgucgugcuggggauagagcauuguaauuauugcucuuc
aacgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguc
ccugcccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuag
ugaggccucaggaucugcuuagagaagggggcaacuccaucucagagcgg
agaauuuggacaaacuuggucauuuagaggaacuaaaagucguaacaagg
uuuccguaggugaaccugcggaaggaucau
..<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<..<<..<<....<<<................<<......<<.
<<<.....>>>.>>......>>........<<<<<............>>>
>><...<<<<<<......((((((..<<<....>>>....<<......>>
>>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>
>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<........
..>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<.
....>>>..>>>..>....>.>.....<<<<<<<<<..<......>..>>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>
>>>.........<<<[[.....<.<<...<<<........<<<<<.<<<<
.....<..>.....>>>>.>>>>>......<<<<.....<<....<<...
....>>....>>.....>>>>....<<<<<.<<.......<<...<....
...>..<<<.....>>>....>>......>>.>>..>>>.........<<
<..<<<<<<<<......)))))).>>>>>>>>.>>>...........<<<
<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>......>.
>>>>>>..>>.......<<....>>...>>>>...>>>>>.>>>...>>>
...>>.>....<<<<<.....<...<<<<.<.....>.>>>>...>..>>
>>>..........<<<.<<..<<..<<<<<<<<.<<<........>>>>>
>>>>>>..>>....<<..]]>>...>>.....>>>.>>>.<<<......<
<<<....>>>>....>>>..]]]].}<<<<<.<<<<<<<..<<.<<<<<<
..<<<.<<<<<<......<<........>>..........<<<<<.....
.<<<<<........<<.<<<........>>>.>>......>>>>>...<<
.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<......>>>
...>>.>>>....<<<<<.<<..<<<<..<<<<<.<<<<<<....>>>>>
>...>>>>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>
>....>>>.>>>...>.>>>>>>>.......>>>>>...>>.>>>>.>>>
.....<<<<<<<......<<.....<<..<<<<....>>>>..>>....>
>.......>>>>>>>...........<<<<<<..........>>>>>>..
........>>>>>>....<<<<<<<<.......>>>>>>>>......>>.
..>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<
<..<.<<..<...<<<<<............................>>>>
>...>..>>.>..>>>.>>>>>>>>...>>.>>>>...>.>>...>....
.<<<<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6woo An active role of the eukaryotic large ribosomal subunit in translation initiation fidelity.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		H74 A80 K82 R83 K86 R94 N97 L99 M101 N102 R104 N105 N106 G107 K108 K109 K111 R114 R168 N171 R182 R187 N188 I189 T191 I192
Binding residue
(residue number reindexed from 1)		H53 A59 K61 R62 K65 R73 N76 L78 M80 N81 R83 N84 N85 G86 K87 K88 K90 R93 R142 N145 R156 R161 N162 I163 T165 I166
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6woo, PDBe:6woo, PDBj:6woo
PDBsum6woo
PubMed
UniProtA0A1L4AA68

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