Structure of PDB 6sg9 Chain FF Binding Site BS01

Receptor Information
>6sg9 Chain FF (length=408) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKRIVVPHRWSEMNRVEHPPLMMKQLFQGVCGGLRWLETKSLAQYLAVRA
IEEGYPSTPGVRSLQVTKQKRLVSYDVLDCTLGSGYHAGAVLENGGPYTR
VVALDCDHDAMHAARDLVEEFGGDRFRFYCCKMSEAKAMFGERSFDAIMI
DGGVSDTQLEDPERGFLLDDEGGHRLDMRFGPQMGVGALEYLNTVSQHTL
VSSLLAYGLLEYGQAMKMSRAITRRKPFVDSREVLTCIEQAGDELPEGGW
RSQGSRRKSPMSWKFLTSLRCIINNEMYELRQGIENALLMLRDDGRLVVF
SRLPWEERLVRGTVDDHPHALLSYVEDISIDDVQIYGFTRHAKMWVITRA
ASSAYALKNTTTLTEEKFRESSVRWLTGMYAGQTHGFPANNFTFENFERK
EWVTLRRN
Ligand information
>6sg9 Chain Cn (length=18) Species: 5702 (Trypanosoma brucei brucei) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RWAAKFYGQVTFGPRNYP
Receptor-Ligand Complex Structure
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PDB6sg9 Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		Q250 H251
Binding residue
(residue number reindexed from 1)		Q197 H198
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0071424 rRNA (cytosine-N4-)-methyltransferase activity
Biological Process
GO:0032259 methylation
GO:0070475 rRNA base methylation
Cellular Component
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6sg9, PDBe:6sg9, PDBj:6sg9
PDBsum6sg9
PubMed31515389
UniProtQ57W60

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