Structure of PDB 6sgb Chain F1 Binding Site BS01

Receptor Information
>6sgb Chain F1 (length=889) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEGAMHKPGESGLQAGSSTTIAGKETWSQFSTKMRYGRRRIRVIDVAAKM
SYEYQMLRKMCKRRPAMRQWAVRDDFCDMNPGVVIMSPSMQAAFMKVFRM
KEKGLIRQCLRDIVPVIEYRNREEPARLKRSQAKLRFRIRQRLLKFQRQL
AVANAIASRSVLYSTNDAIGYFLFRGAAMYAGMHRVFFELSKQLPHFVPK
TMLDFGAGTGTAILVAKEVYDPGSLAYPLYRSLRQTMQGNDSSRTHQLSE
LRYDLKRLQRNNEEKKKVRFMAVAALLERGEVDPADLPEDLKREIAEVAT
AAATAKKDRLVREAHARYRDVVDGTEWESGDPLGEVRASTEDPEDVIDGE
QGDGGDDGEAAKGRPKTWWEKLIDVENETARTRAARRLRPLQEVTAVEPS
PGMMEIGTMVLHDDVPNVTWKRYLLPEDEAIQHDLVVAAYSLSEIATSEN
RRRIVQQLWKMTKGVLVFVEFANLNNFNILMEARDWILEEKDVGLWDWQP
TIVAPCPHEHRCPLRHCKTGVKRKRMRICSTEAHYRSTFVEVWARHMPLK
VGIEPISYLILARNELVPERAERRREQLKKAEEMKRRERDVKQQQLHEAS
LAVKDVVFERLSDEALHRVQSSVPQPLTDIDSATSTSLLKDLKDGATSTG
EIGHMPTDVPRLVKTGNTRHNRLIFPLQFPPATHKFNRAFVDAGYQRQRA
ITPAEMLVVRQEVEQLQQRVMRAAPKYLRVVRDPRCHGKVQADFCTPEGD
LVSGRVYRRFYGDRNRVSAHSTMRWQHIGGWKLLKRIRRGSLFPHNVPLY
AVTKHAQIDFPNTLLDTKHSTVEQTAMQYNDPMEISEQQWADAVRRAKIR
TVQHTKNALPFAAKKRAAQRALQVRRRNVRLEMSGNRRR
Ligand information
>6sgb Chain Cn (length=27) Species: 5702 (Trypanosoma brucei brucei) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RWAAKFYGQVTFGPRNYPYPSSRWLAR
Receptor-Ligand Complex Structure
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PDB6sgb Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		D157 R225 L229 Q232 R233 L235 A236 V237 N239 S245 L247
Binding residue
(residue number reindexed from 1)		D112 R140 L144 Q147 R148 L150 A151 V152 N154 S160 L162
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008168 methyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6sgb, PDBe:6sgb, PDBj:6sgb
PDBsum6sgb
PubMed31515389
UniProtQ385R2

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