Structure of PDB 8uu8 Chain F Binding Site BS01

Receptor Information
>8uu8 Chain F (length=175) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NRLKDQYLKEIVPALMSKFNYDSVMEVPKIDKIVINTGVGDATANAKVLD
SAVEELALITGQKPVITKAKNSIAGFRLREGMPIGAKVTLRGERMYDFLD
KLVTVSLPRVRDFRGVSKKAFDGRGNYTLGVREQLIFPEIDYDQVSKVRG
MDVVIVTTAKSDEESHELLTQLGMP
Ligand information
>8uu8 Chain A (length=2901) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaag
aaggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguug
auccagagauuuccgaaugggggaacccacuaucuuuagucggauaguau
ccuuacgugaauacauagcgugaggaaggcagacccagggaacugaaaca
ucuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggc
gagcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguugua
ggacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugg
aaaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccu
ccagaguggauccugaguacgacggaacacgugaaauuccgucggaaucc
gggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaac
caguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacag
uuccugaaaccgugugccuacaaguaguuagagcccguuaaugggugaua
gcgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguua
agcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaa
guaacaggucguagacccgaaaccaggugaucuacccauguccaggauga
agguaagguaauacuuacuggagguccgaacccacgcacguugaaaagug
cggggaugagguguggguagcggagaaauuccaaucgaacuuggagauag
cugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucau
ggagguagagcacuguuuggacuaggguaccgaauucagauaaacuccga
augccauguacuuauacucgggagucagacugcgagugauaagauccgua
gucgaaagggaaacagcccagaccaccaguuaagguccccaaauauaugu
uaaguggaaaaggaugugggguugcuuagacaaccaggauguuggcuuag
aagcagccaccauugaaagagugcguaauagcucacuggucgagugaccc
cgcgccgaaaauguaccggggcuaaacauauuaccgaaacuguggaugaa
ccuagguucgugguaggagagcguucuaagggcggugaagucagaccgga
aggacugguggagcgcuuagaagugagaaugccgguaugaguagcgaaag
aagggugagaaucccuuccaccgaauaucuaagguuuccugaggaaggcu
cguccgcucaggguuagucgggaccuaagccgaggccgauaggcguaggc
gauggacaacagguagagauuccuguaccagugcuaauuguuuaaccgau
ggggugacacagaaggauagggaaucgcacgaauggaaaugugcguccaa
gcagugagugugagaaguaggcaaauccgcuucuugcgaagcaugagcug
ugauggggaaguacggaaguuccugauuucacgcugucaagaaaagccuc
uaggaagaguaguacugcccguaccgcaaaccgacacagguagaugagga
gagaauccuaaggugagcgagagaacucucguuaaggaacucggcaaaau
gaccccguaacuucgggagaaggggugcucuauuagggugcaagcccgag
agagccgcagugaauaggcccaggcgacuguuuagcaaaaacacaggucu
cugcaaaaccguaaggugacguauaggggcugacgccugcccggugcugg
aagguuaagaggagugcuuagcuucggcgaagguacgaauugaagcccca
guaaacggcggccguaacuauaacgguccuaagguagcgaaauuccuugu
cggguaaguuccgacccgcacgaaaggcgcaacgaucugggcacugucuc
aacgagagacucggugaaauuauaguaccugugaagaugcagguuacccg
cgacaggacggaaagaccccguggagcuuuacugcaaccugauauggaau
guuuguaccgcuuguacaggauagguaggagccgaagagacgugugcgcu
agcauacgaggaggcaauggugggauacuacccuggcuguaugaccauuc
uaacccgccacgcuaagcgcguggggagacagugucaggugggcaguuug
acuggggcggucgccuccuaaagaguaacggaggcgcccaaagguucccu
cagaauggauggaaaucauucgcagaguguaaaggcacaagggagcuuga
cugcgagacugacaagucgagcagggacgaaagucgggcuuagugauccg
gugguuccgcauggaagggccaucgcucaacggauaaaagcuaccccggg
gauaacaggcuuaucucccccaagaguccacaucgacggggagguuuggc
accucgaugucggcucgucgcauccuggggcuguagucggucccaagggu
ugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucgu
gagacaguucggucccuauccgucgcgggcgcaggaaauuugagaggagc
uguccuuaguacgagaggaccgggauggacacaccgcugguguaccaguu
guuccgccaggagcaucgcuggguagcuauguguggcagggauaaacgcu
gaaagcaucuaagcgugaagccccccucaagaugagauuucccauuucuu
cggaaaguaagaucccugaaagaugaucagguagauagguuuggagugga
aguguagcgauacauggagcggacaaauacuaaucgaucgaggacuuaac
c
<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<....
..<<<<<<.[...((.>>>.....<<<<<<<..<<<))...].>>>....
.>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....
>>......>>>>>.>.........<<....>>..<<<<<......<<...
..>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<
<<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<...
...>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>
>>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......
<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]..........
.....<<....>>....]].........<<<<....>>>>..........
...}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>
>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<..
.<<.......>>...>>>...<<....>>..<<<<.....>>>>......
>>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>
>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..
>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<
<<.....<<<...<<<<<<<<...<<...>>...>>>>>>>>..>>.>..
...>>>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>>
>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<
...........<<..<<<<<<<<<<<......<<<<<.<<<..<<<<...
....>>>>..>>>.........<<......>>...>>>>>..>>>>>>>>
>>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<<
<<..>>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<<...
.>>.>>>>>...>>.>>>>>>>..>.....>>>>>><......<<....<
<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<..
...>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>
...>>...<<<<<........>>>>>))<<<<<<<<.<<......<<...
<<<<<...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.<<..
<<<<<..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..>>>>
>...>>.............>>>>>...>>>...>>>>........>>>>>
..>>..>>.>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<
.....>>>>..>>>>..<<<<....<<<<<<<<.<<.........<....
.<<<<<.....<..>......>>>>><<<<<....<<<<....>>>>...
>>>>>............<<<<<<<<<..<<<.........>>>..<<<<<
<<.....<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<<<
..<<<<..<<...<<<<<<.<<....>>..>>>>>>...>>..>>>>>>>
>>..>>>>><<<<<<.......>>>>>>........<...........<<
<<<.......>>>>>.....>....>>>>...>>.>>>>>>>..>..>>.
>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<
<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<
<.<<<<<<.<<<...........<<<<<..<<<.......<<<<<<<...
.>>>>>>>....>>>............>>>>>..>>>.>>>>>>.>>>>>
....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<
<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<.
..<<<<<.<......>>>>>>.....<<.[.(((>>....>>>>>>>...
<<<<..<<<<....>>>>..>>>>.<<<....>>>.>>)))]......<<
<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>
.......<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>
.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.
<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<..
..>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<
<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<
<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<
...........>>>>>...>>>>.>>>>.......>>>>>>>..<<<<..
..>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<...
.<<<<<....>>>>>...>>...>>>>>.>>>...>>>>....>>>>>>>
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8uu8 Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		N37 G39 G41 T68 A70 F77 L79 I85 K88 A121 F122 D123 R125 T129 L130 G131 R133 R150 G151 D153
Binding residue
(residue number reindexed from 1)		N36 G38 G40 T67 A69 F76 L78 I84 K87 A120 F121 D122 R124 T128 L129 G130 R132 R149 G150 D152
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8uu8, PDBe:8uu8, PDBj:8uu8
PDBsum8uu8
PubMed38407413
UniProtA0A0U5AWX6

[Back to BioLiP]