Structure of PDB 8phj Chain F Binding Site BS01

Receptor Information
>8phj Chain F (length=103) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYP
INKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEAS
PMV
Ligand information
>8phj Chain A (length=1503) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaa
cacaugcaagucgaacgguaacaggaaguuugcugacgaguggcggacgg
gugaguaaugucugggaaacugccugauggagggggauaacuacuggaaa
cgguagcuaauaccgcauaacgucgcaagaccaaagagggggccucuugc
caucggaugugcccagaugggauuagcuaguaggugggguaacggcucac
cuaggcgacgaucccuagcuggucugagaggaugaccagccacacuggaa
cugagacacgguccagacuccuacgggaggcagcaguggggaauauugca
caaugggcgcaagccugaugcagccaugccgcguguaugaagaaggccuu
cggguuguaaaguacuuucagcggggaggaagggaguaaaguuaauaccu
uugcucauugacguuacccgcagaagaagcaccggcuaacuccgugccag
cagccgcgguaauacggagggugcaagcguuaaucggaauuacugggcgu
aaagcgcacgcaggcgguuuguuaagucagaugugaaauccccgggcuca
accugggaacugcaucugauacuggcaagcuugagucucguagagggggg
uagaauuccagguguagcggugaaaugcguagagaucuggaggaauaccg
guggcgaaggcggcccccuggacgaagacugacgcucaggugcgaaagcg
uggggagcaaacaggauuagauacccugguaguccacgccguaaacgaug
ucgacuuggagguugugccggcguggcuuccggagcuaacgcguuaaguc
gaccgccuggggaguacggccgcaagguuaaaacucaaaugaauugacgg
gggcccgcacaagcgguggagcaugugguuuaauucgaugcaacgcgaag
aaccuuaccuggucuugacauccacggaaguuuucagagaugagaaugug
ccgaaccgugagacaggugcugcauggcugucgucagcucguguugugaa
auguuggguuaagucccgcaacgagcgcaacccuuauccuuuguugccag
cgguccggccgggaacucaaaggagacugccagugauaaacuggaggaag
guggggaugacgucaagucaucauggcccuuacgaccagggcuacacacg
ugcuacaauggcgcauacaaagagaagcgaccucgcgagagcaagcggac
cucauaaagugcgucguaguccggauuggagucugcaacucgacuccaug
aagucggaaucgcuaguaaucguggaucagaaugccacggugaauacguu
cccgggccuuguacacaccgcccgucacaccaugggaguggguugcaaaa
gaaguagguagcuuaaccuucgggagggcgcuuaccacuuugugauucau
gacuggggugaagucguaacaagguaaccguaggggaaccugcgguugga
uca
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....
<<<.<<<..<<<..<<.<...<<<<<<.>>>.>>>.>..>>>>>......
<<.......<<<<<<<..<<...<<<<<<<.<.<<.....<<<<<.....
.>>>>>......>>.>.....<<<....>>>....<<<<<<.>>>>>>.>
>>>>>>..>>.>>>>>>><<<....<<<..<<<<<<<.........>>>>
>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<.
<.........>>>>>>.<<<<....>>>>...>>>>>>.........<<<
....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<<.
.>>>>>.....>>>>...<.<<<<<......<.<<<<<<<<.......>>
>>>>>>.>........>>>>>....>..<<<<<(((...<<<<<.....<
<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((
.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<....
.>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<
<....<<<<<<<<...<<<......>>>......>>>>>>>>........
...<<....>>.>>>>>>>..>>>>.>>>>...>>>...>>>>....<<<
<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........<
<<<<<.<<<<<<<<<<<<..>>>>>>>>>>>>..<<..))>>.....>>>
>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<.
<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>...
.......<<<<<<<......<<<<<<<..<<<<<<<....>>>>>>>...
.....>>>>>.>>.<<<.<<<..<<<<<<.......<<<<<<<<<....>
>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<<..
<<<.....>>>>>....>>>>>>>.....<<<<<.....>>>>>......
..>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>>>
>>>>.....<<<<<<<.....<<<..<<...<<<....>>>...>>....
>>>.....>>>>>>>......<....<<<<<<<........>>>>>>>..
..>.....>>>>>>....<<<<<<<.........>>>>>>>......>>.
..>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<.
...<<<<<<.<<<<..<<....>>.>>>>>>>>>>...>>>>>>>>>>>>
..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>>...
...
Receptor-Ligand Complex Structure
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PDB8phj Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling
Resolution3.67 Å
Binding residue
(original residue number in PDB)		R2 K53 R79 R86 V89 M90 R91
Binding residue
(residue number reindexed from 1)		R2 K53 R79 R86 V89 M90 R91
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0048027 mRNA 5'-UTR binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8phj, PDBe:8phj, PDBj:8phj
PDBsum8phj
PubMed38033086
UniProtP02358|RS6_ECOLI Small ribosomal subunit protein bS6 (Gene Name=rpsF)

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