Structure of PDB 8om4 Chain F Binding Site BS01

Receptor Information

>8om4 Chain F (length=131) Species: 4932 (Saccharomyces cerevisiae)

MLYELIGLVRITNSNAPKLEAKELSSTIGKLIIQNRGVVRDIVPMGIRYL
PKIMKKDQEKHFRAYHFLMLFDSSAAVQSEILRTLKKDPRVIRSSIVKVD
LDKQLDRASSLHRSLGKKSILELVNEDYQSI

Ligand information

>8om4 Chain r (length=1487)

auaagaauaugauguugguucagauuaagcgcuaaauaaggacaugacac
augcgaaucauacguuuauuauugauaagauaauaaauaugugguguaaa
cgugaguaauuuuauuaggaauuaaugaacuauagaauaagcuaaauacu
uaauauauaaaaaggauauauaauauauuuaucuauagucaagccaauaa
ugguuuagguaguagguuuauuaagaguuaaaccuagccaacgauccaua
aucgauaaugaaaguuagaacgaucacguugacucugaaauauagucaau
aucuauaagauacagcagugaggaauauuggacaaugaucgaaagauuga
uccaguuacuuauuaggaugauauauaaauauauauauauaaauugauua
aaaauaaaauccauaaauaauuaaaauaaugauauuaauuaccauauauu
uuuauauggauauauuuuaauaguccugacuaauauuugugccagcaguc
gcgguaacacaaagagggcgagcguuaaucauaaugguuuaaaggauccg
uagaaugaauuauauauuauaauuuagaguuaauaaaauuaauuaaagaa
uuauaauaguaaagaugaaauaaauaauuauaagacuaauauaugugaaa
auauuaauuaaauauuaacugacauugagggauuaaaacuagaguagcga
aacggauucgauacccguguaguucuaguaguaaacuaugaauacaauua
uuuauauauauauauauaaauaauaaaugaaaaugaaaguauuccaccug
aagaguacguuagcaauaaugaaacucaaaacaauagacgguuacagacu
uaagcaguggagcauguuauuuaauucgauaauccacgacuaaccuuacc
auauuuugaauauuauaauaauuaaauuauuauauuacaggcguuacauu
guugucuuuaguucgugcugcaaaguuuuagauuaaguucauaaacgaac
aaaacuccauauauauaauuuuaauuauauauaauuuuauauuauuuauu
aauauaaagaaaggaauuaagacaaaucauaaugauccuuauaauauggg
uaauagacgugcuauaauaaaaugauaauaaaauuauauaaaauauauuu
aauuauauuuaauuaauaauauaaaacauuuuaauuuuuaauauauuuuu
uuauuauauauuaauaugaauuauaaucugaaauucgauuauaugaaaaa
agaauugcuaguaauacguaaauuaguauguuacggugaauauucuaacu
guuucgcacuaaucacucaucacgcguugaaacauauuauuaucuuauua
uuuauauaauauuuuuuaauaaauuuauuaauuuauauuuauuuauauca
gaaauaauaugaauuaaugcgaaguugaaauacaguuaccguaggggaac
cugcggugggcuuauaaauaucuuaaauauucuuaca

....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<
.<<<..<<<..<<<<<<<<<<<<.....>>>>>>>>>>..>>>>>.....
<<<........<<<<<.<<.........<<<<<<<<.<<<<.......>>
>>...........<<<<<<<<.>>>>>>>>.>>>>>>>>....>>>>>>>
<<<....<<<..<<<<<<<<........>>>>>>>>>>>......>>>..
<<<<.<<<<....>>>>...>>>>.>>><<<<<<.........>>>>>><
<<<.....>>>>..>>>>>>.........<<<....<<<<....>>>>..
>>>..>>.>>>>>>.<<<<..<<<<<<........>>>>>>..<<.....
.>>.....>>>>..<<<<<<<<..............>>>>><<<<<<<..
..>>>>>>><<..>>>>>....<<<<<(((.....<<<<.....<<.)))
>>.......>>>>.>>>>>..>>>>>>>>>.....<<<((.....<<<<.
..<.<<.<<<<<<<...>>>>>>>...<<<<<<<<...<<<<<<<<<<..
<<<<<<<...................>>>>>>>..>>.......<<....
>>.>>>>>>>>.>>>>>>>>...>>>...>>>>....<<<<<<...<<..
.<<<<.........>>>>...>>>>>>>>..........<<<<<<.<<<<
<<<<<<<<<..>>>>>>>>>>>>>..<<..))>>....>>>>>>.>>>.<
<.......<<<<....>>>>.....>>..)))).]<<.<<...<<<<...
..<<<<<<..<<<<<<<<<<......<<........>>..........<<
<<<<<.....<<.<<<<<<<<<<.>>>>>>>>>>.>>.<<<.<<<..<<<
<<<<<<<<..<<<<<<<<<....>>>....<<......>>....>>>>>>
.....<<<.<<<<<<<<........>>>>>>>>..<<<<<<<<<.....>
>>>>>>>>....>>>...>>>>>.>>>...>>>>>>>>>...>>>>>>>.
..>>.>>>>>>>>.....<<<<<<........<<<..<<..<<<<<<...
...>>>>>>..>>....>>>......>>>>>>......<<<<<.<....>
.>>>>>..........<....<<<<<<<........>>>>>>>....>..
...>>>>>>....<<.<<<<<.........>>>>>>>...........>>
>>..>>..>>....<.<<<.<.<<<<<<<<..<<<<<<<<<.<<<...<<
<..<<<.<<<<<...<<<<<<<..>>>>>>>...>>>>>>>>..>>>..>
>>>>>>>>>>>..>>>>>>>>..>.>>>..>.....<<<<<<<<<....>
>>>>>>>>.............................

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8om4 METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
• Resolution: 2.32 Å
• Binding residue (original residue number in PDB): Y3 K52 K55 A75 K86 R93 I96 V97 K98 K103
• Binding residue (residue number reindexed from 1): Y3 K52 K55 A75 K86 R93 I96 V97 K98 K103

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0070181 small ribosomal subunit rRNA binding

Biological Process

• GO:0006412 translation
• GO:0032543 mitochondrial translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0005763 mitochondrial small ribosomal subunit
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8om4, PDBe:8om4, PDBj:8om4
• PDBsum: 8om4
• PubMed: 38199006
• UniProt: P28778|RT06_YEAST Small ribosomal subunit protein bS6m (Gene Name=MRP17)