Structure of PDB 8jla Chain F Binding Site BS01

Receptor Information
>8jla Chain F (length=78) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTE
HAKRKTVTAMDVVYALKRQGRTLYGFGG
Ligand information
>8jla Chain I (length=156) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gctaggatcacaatcccggtgccgaggccgctcaattggtcgtagacagc
tctagcaccgcttaaacgcacgtacggaatccgtacgtgcgtttaagcgg
tgctagagctgtctacgaccaattgagcggcctcggcaccgggattgtga
tcctag
Receptor-Ligand Complex Structure
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PDB8jla Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Resolution3.44 Å
Binding residue
(original residue number in PDB)
R45 I46 G48 R78 K79 T80
Binding residue
(residue number reindexed from 1)
R21 I22 G24 R54 K55 T56
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:8jla, PDBe:8jla, PDBj:8jla
PDBsum8jla
PubMed37718728
UniProtP62805|H4_HUMAN Histone H4 (Gene Name=H4C1)

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