Structure of PDB 8jib Chain F Binding Site BS01

Receptor Information
>8jib Chain F (length=657) Species: 7159 (Aedes aegypti) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNYKKNLLLLYDRPREPIFMGKGKSVFDVPDNYLTDRYRPIGPEIQNRFG
ELAEERIPVRSIALPDLRIPMSLGRQEQFSLFIPRHRKIAARLIDIFMGM
RNIEELQSCAVFARDRINPYLFNYALSVALLHRRDTKNLDLPSVVEVFPD
KYVDSRVFEQIREEATVVPEGMRMPIVIPKDFTASDLDEEHRLWYFREDI
GVNLHHWHWHLVYPFEASNRAIVDKDRRGELFYYMHSQLIARYNFERFCN
RLQRVKRLNNLREPIAEGYFPKLDSLVASRTWPGRVDNAVIKDLNRELDQ
IKQDVSDLERWIDRIYEAVHQGYVVDESGNRIFLDEEKGIDILGNIIESS
ILSPNRQLYGDMHNVGHVFLSYTHDPDHRHLESFGVMGDVATAMRDPVFY
RWHSFIDDIFQEHKIKLPAYTKSQLTYEGISVTGIIVQSEGAPVNTLHTY
WQQSDVDLSRGMDFVPRGNVFARFTHLQHAPFQYVIQIDNTSDAQRMGFV
RIFMAPKNDERGQPMLFRDQRLFMVEMDKFLVALRPGANRIRRRSNESTV
TIPFERTFRCGWPAHMLVPKGLPEGFPADLFVMVSNYEDDRVVQDLVGTC
NDYCGVRDRLYPDRKAMGFPFDRLARTGVDRLSNFVTPNMAIQSVNVIHI
DKTVPRT
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain8jib Chain F Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8jib Mosquitoes have evolved two types of prophenoloxidases
Resolution3.15 Å
Binding residue
(original residue number in PDB)		H206 H210 H236
Binding residue
(residue number reindexed from 1)		H206 H210 H236
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0004503 tyrosinase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006582 melanin metabolic process
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8jib, PDBe:8jib, PDBj:8jib
PDBsum8jib
PubMed
UniProtQ16G28

[Back to BioLiP]