Structure of PDB 8it0 Chain F Binding Site BS01

Receptor Information
>8it0 Chain F (length=450) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRNKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLDKGVDFWSTIE
KEIRENTCKFLIVSSTAGNKREGVLKELAVATKVKKHLQDDMFIIPLAID
ENLSYDDINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPKKPPDHSKS
NLLYQQIFLHDKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDV
RTLAFPAIRYKEYLCTFAWEYDFIHQLPKTETYNGQESIRISTSDILSGR
YDTDFIRNYECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKL
EKDKFEKIKLVGKQKNKYWHFGISAAGKLYPSPVLMVSSHIIFTMDGINL
IKSKSIQHSSRRKQGKNWWNDKWREKLLAFIRFLSDDQNAIYLNVGSEEK
ILISNKPLKFFGKMSYVTPSEVTLEEESVLADINNFEEDTEDLDELEDIE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8it0 Nucleic acid-triggered NADase activation of a short prokaryotic Argonaute.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R201 R263 Q267 H358 S359 R362 K363 K366 N434 N435 E438 E441 D442 E445
Binding residue
(residue number reindexed from 1)		R201 R263 Q267 H358 S359 R362 K363 K366 N434 N435 E438 E441 D442 E445
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007165 signal transduction

View graph for
Biological Process
External links
PDB RCSB:8it0, PDBe:8it0, PDBj:8it0
PDBsum8it0
PubMed37783228
UniProtA0A1I7NFG5

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