Structure of PDB 8iht Chain F Binding Site BS01

Receptor Information
>8iht Chain F (length=82) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAV
TYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Ligand information
>8iht Chain I (length=158) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ttactggccgccctggagaatcccggtgccgaggccgctcaattggtcgt
agacagctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgttt
taaccgccaaggggattactccctagtctccaggcacgtgtcagatatat
acatcctg
Receptor-Ligand Complex Structure
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PDB8iht Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
Resolution3.72 Å
Binding residue
(original residue number in PDB)		R45 I46 G48 R78 K79
Binding residue
(residue number reindexed from 1)		R25 I26 G28 R58 K59
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8iht, PDBe:8iht, PDBj:8iht
PDBsum8iht
PubMed37845487
UniProtP62799|H4_XENLA Histone H4

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