Structure of PDB 8ify Chain F Binding Site BS01

Receptor Information
>8ify Chain F (length=595) Species: 9874 (Odocoileus virginianus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
STTEEQAKTFLEKFNHEAEDLSYQSSLASWNYNTNITDENVQKMNEARAK
WSAFYEEQSRMAKTYSLEEIQNLTLKRQLKALQQSGTSVLSAEKSKRLNT
ILNTMSTIYSTGKVLDPNTQECLALEPGLDDIMENSRDYNRRLWAWEGWR
AEVGKQLRPLYEEYVVLENEMARANNYEDYGDYWRGDYEVTEAGDYDYSR
DQLMKDVENTFAEIKPLYEQLHAYVRAKLMDTYPSYISPTGCLPAHLLGD
MWGRFWTNLYSLTVPFKHKPSIDVTEKMKNQSWDAERIFKEAEKFFVSIS
LPHMTQGFWDNSMLTEPGDGRKVVCHPTAWDLGKGDFRIKMCTKVTMDDF
LTAHHEMGHIQYDMAYAAQPYLLRDGANEGFHEAVGEIMSLSAATPHYLK
ALGLLEPDFYEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIP
KEQWMEKWWEMKREIVGVVEPLPHDETYCDPACLFHVAEDYSFIRYYTRT
IYQFQFHEALCKTANHEGALFKCDISNSTEAGQRLLQMLSLGKSEPWTLA
LESIVGIKTMDVKPLLNYFEPLFTWLKEQNRNSFVGWSTEWTPYS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8ify Chain F Residue 706 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8ify Structural basis of SARS-CoV-2 binding to ACE 2 receptor of white-tailed deer, Odocoileus virginianus
Resolution2.55 Å
Binding residue
(original residue number in PDB)		W478 P500
Binding residue
(residue number reindexed from 1)		W459 P481
Annotation score1
Enzymatic activity
Enzyme Commision number 3.4.-.-
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0008237 metallopeptidase activity
GO:0008241 peptidyl-dipeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ify, PDBe:8ify, PDBj:8ify
PDBsum8ify
PubMed37676003
UniProtA0A6J0Z472

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