Structure of PDB 8i02 Chain F Binding Site BS01

Receptor Information
>8i02 Chain F (length=235) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IRNVDYCSACGGRGLFICCEGCPCSFHLSCLEPPLTPENIPEGSWFCVTC
SIKSHHPPKHPLSIWSQLYDWIDSQNPSQYRLPDDLVHYFHGISRGDTGA
YKETEGEITNLAYCGYCSKPSMGACWVYGCQLCDTFYHKNCKEHAKKCSH
DSIGKKGMRVPFPRLPVSCLYKVSEDGLIKDFLYAIGIEAKKFNNERKKR
ELEVIPPDVKSALLPARTHPNLPIALRTLFNKART
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8i02 Chain F Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8i02 Two assembly modes for SIN3 histone deacetylase complexes.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
C135 C137
Binding residue
(residue number reindexed from 1)
C22 C24
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0045815 transcription initiation-coupled chromatin remodeling
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005829 cytosol
GO:0032221 Rpd3S complex
GO:0032991 protein-containing complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8i02, PDBe:8i02, PDBj:8i02
PDBsum8i02
PubMed37076472
UniProtQ09819|YAC5_SCHPO Uncharacterized protein C16C9.05 (Gene Name=SPAC16C9.05)

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