Structure of PDB 8fru Chain F Binding Site BS01

Receptor Information
>8fru Chain F (length=221) Species: 941442 (Giardia intestinalis assemblage A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRDIRSAAERATEKEKRAALVKDHAVKSAQVYARYYIDLVESEKKARENA
LKNNQLYVPDEPKVYLVVRIRGIVGVAPKVRTILSLLRLRQINNAVFMRC
NKATLNALRIVDHYVTYGEPTVETIRNLIYKRGFAKVNGQRIPIVDNNLI
DEQLSKHNILCAEDLVHEIFTCGSSFKEANNFLWPFQLNSAALKDKRNNF
AEGGDFGYRGKYINEFVARMI
Ligand information
>8fru Chain 3 (length=117) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aguucggccauccuacggcggaaacuccuuaacucguuccgaauuaagaa
gagaagcgccgucaggccccgccaguacugcgaucggagacgucguggga
acacggggugccgaacu
<<<<<<<<....<<<<<<<<.....<<<<<...............>>>..
>>....>>>>>>.>><<<<<<......<<<<<<.<<....>>>>>>>>..
...>>>>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB8fru The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.
Resolution2.49 Å
Binding residue
(original residue number in PDB)		R211 E216
Binding residue
(residue number reindexed from 1)		R197 E202
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fru, PDBe:8fru, PDBj:8fru
PDBsum8fru
PubMed38242118
UniProtA8BRY6

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