Structure of PDB 8euy Chain F Binding Site BS01

Receptor Information
>8euy Chain F (length=240) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASIFAPESLLKKTKAQKQSREQIVAAAAEKKSARQKKRELIAKRAEAYEA
EYRAAEREQIELARKARAEGNYFVPHEPKLIFVVRIRGINNIPPKARKIM
QLLRLLQINNGIFVKFNKAIKEMLQVVEPYVTYGIPNHKTVRELIYKRGF
GKVNKQRIPLSDNAIIEAALGKYSILSVEDLIHEIYTVGPNFKQAANFLW
PFKLSSPLGGWRERKFKHFIEGGDAGKRDEHINGLVQKML
Ligand information
>8euy Chain 1 (length=1433) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucaaaucagguaggacuacgcgcugaacaauaagcgcaggaaaa
gaaaauaaccaugauucccucaguaacggagugaagcgggaaaagcucaa
auuugaaaucuggcaacauuucuuuuguuguccgaguuguaauuucaaga
agcugcuuugaguguagacgaucggucuaaguuccuuggaacaggacguc
agagagggugagaaccccgucuuuggucgauuggauaugccauauaaagc
gcuuucgaagagucgaguuguuugcagcucuaaaugggugguaucaucua
aagcuaaauauuggcgagagaccgauagcgaacaaguagagugaucgaaa
gaugaaaagaacuuugaaaagagaguuaaauaguacgugaaauugcugaa
agggaagcauuggaaaucagucuuaccugggugagaucaguagucucucg
agacuaugcacucugaaccugugguaggucagcaucaguuuucgggggcg
gaaaaagaauaagggaagguggcguguuuauagccuuguuguaauacguc
cacuggggacugaggacugcggcuucgugccaaggaugcugacauaaugg
uuuucaauggcccgucuugaaacacggaccaaggagucuagcaucuaugc
gaguguuugggugaugaaaacccauccgcgaagugggaacgcccuugugg
cgugcaccagagcauagcuguugggacccgaaagauggugagaaccaucu
aguagcugguuccugccgaaguuuccggauagcagaaacucagaucaguu
uuaugaguauguaaaaugagaguuucuagugggccauuuuugguaagcag
aacuggcgaugcgggaugaaccgaacgugagguuaaggugccggaaugua
cgcucaucagacgaaaagguguuaguucaugaacuagcccugggcgcuua
agcguacuacccauaccucaccgucuggguuagcuuugagaagcucagac
gaguaggcaggcguggagguuugugacgaagccuugggcgugagccuggg
ucgaacagccucuagugcagaucuugguggaaguagcucuagcgaaacca
cagccuggggaacgggccaggucgucgcaaugguaauucaacuuaguacg
agaggaaccguugauucagaucauugguauuugcgcggagcuaucaucug
cuggauaacggcugaacgccucuaagccagaauccgugccagaaagcgac
gagguccgcauauguauaaaaauagagguaggcuacucuccuguaucgua
gaagaugggcgaugguugaugaaacggaaguguuuuauugacuuguccau
gaaauuccaugugcggaaucgaauccauugcauacgacuuuaauguggaa
cgggguauugagauucuuuguucccaagauuug
........................<<<<<<........>>>>>.>.....
....<<....>>..<<<<<......<<...>>.....>>>>>..<<<..<
<.......<<.<<<<<<<.......>>>>>>>.>>.......>>....<<
<<<.<<<<<..<<<<<..<<<<<<<<<.....<<<<......>>>>.((.
.....<<<.....))>>>......>>>>>>>>>..>>>>>.....>>>>>
>>>.>>........<<<<<<<..>>>>>>>.....<<<<<<..>>>>>>.
.>>>..................................<<....>>....
...........<<<<....>>>>...........................
.......<<<<<<<<<<<<.....<<<.<<<<.<<<.<<.<<<<<<<..>
>>>>>>>>...>>>..>>>>..>>>..<<<<<<<.<<<<<<<<<<<<<<<
.......<<<<<<<.......<..>........>>>>>>>......>>>>
>.>>>>>>>>>>........<<<.....>>>.....>>>>>>>....>>>
>>>>>>>>>..<<<<........>>>><<<<<<....<<<<<<.<<<<<<
..<<<...<<<<.......>>>>...>>>...<<<....<<<....>>>.
....>>>....>>>>>>.>>>>>>..<<.<...<<<<<<....>>>>>>.
.....>.>>..<<<<<<....<.<<..>>.><<<<<<<<<<...<<<.<<
<<<<<....>>>>>>>>>>>>>>>>>>.>>..<<<<.<<<<<.....>>>
>>.>>>>....<<<......>>>...<<<<<<<...<<<(((.....<<<
<<<......<......<<<.<<<<<<<<..>>>>>>>>>>>.))).>...
.>>>>>>.>>>...>>>>>>><<<<<<<<<............>>>>>>>>
>....>>>>>><.<<<<<<<..<<......<<<<.<<<<....>>>>>>>
>...>>.>>>>>>>..>.....>>>>>><<.....<<....>>....>>.
...<<<<<........>>>>><<<<<<<..<<<<.<.<<<<<........
.........>>>>>.><<<<<...<<<<....<..>...>>>>..>>>>>
.<<<<....<<<<...........>>>>....>>>>.>>>>....>>>>>
>><.<<<<<<<....<<.......<<<<.<<.>>..>>>>....>>....
....<<<<<.....<<<<<<<<<<<......>>>>>>>>>>>...>>>>>
..........>>>>>>>.><<<<<<.....................<<<<
<<<...<<....>>..>>.>>>>>...>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8euy Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
K22 R44 R48 R67 I70 R74 R77 R97 G98 I99 N100 P104 K105 K108 I109 L112 R114 Q117 N119 K128 E132 N147 K149 R152 K157 R158 Q166 R167 K203 N207 K213 L214 S215 S216 P217 L218 G219 G220 W221 E223 R224 K225 F226
Binding residue
(residue number reindexed from 1)
K12 R34 R38 R57 I60 R64 R67 R87 G88 I89 N90 P94 K95 K98 I99 L102 R104 Q107 N109 K118 E122 N137 K139 R142 K147 R148 Q156 R157 K193 N197 K203 L204 S205 S206 P207 L208 G209 G210 W211 E213 R214 K215 F216
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8euy, PDBe:8euy, PDBj:8euy
PDBsum8euy
PubMed36423630
UniProtP25457|RL7B_SCHPO Large ribosomal subunit protein uL30B (Gene Name=rpl702)

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