Structure of PDB 8eo4 Chain F Binding Site BS01

Receptor Information
>8eo4 Chain F (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKG
NRKKMTYQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLGRGGLA
Ligand information
Receptor-Ligand Complex Structure
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PDB8eo4 DNA selection by the master transcription factor PU.1.
Resolution1.24 Å
Binding residue
(original residue number in PDB)
S203 K206 R230 R233
Binding residue
(residue number reindexed from 1)
S35 K38 R62 R65
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function

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Biological Process
External links
PDB RCSB:8eo4, PDBe:8eo4, PDBj:8eo4
PDBsum8eo4
PubMed37352101
UniProtP17947|SPI1_HUMAN Transcription factor PU.1 (Gene Name=SPI1)

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