Structure of PDB 8ekv Chain F Binding Site BS01
Receptor Information
>8ekv Chain F (length=91) Species:
9606
(Homo sapiens) [
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KIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKG
NRKKMTYQKMARALRNYGKTGEVKKVKKKLTYQFSGEVLGR
Ligand information
>8ekv Chain C (length=16) [
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aataagcggatgtggg
Receptor-Ligand Complex Structure
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PDB
8ekv
DNA selection by the master transcription factor PU.1.
Resolution
1.62 Å
Binding residue
(original residue number in PDB)
S203 K206 R230 R233 K243 K247 L248
Binding residue
(residue number reindexed from 1)
S35 K38 R62 R65 K75 K79 L80
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003700
DNA-binding transcription factor activity
GO:0043565
sequence-specific DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
GO:0006357
regulation of transcription by RNA polymerase II
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Molecular Function
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Biological Process
External links
PDB
RCSB:8ekv
,
PDBe:8ekv
,
PDBj:8ekv
PDBsum
8ekv
PubMed
37352101
UniProt
P17947
|SPI1_HUMAN Transcription factor PU.1 (Gene Name=SPI1)
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