Structure of PDB 8d3l Chain F Binding Site BS01

Receptor Information
>8d3l Chain F (length=98) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSMLVLITYDVQTSSMGGTKRLRKVAKACQNYGQRVQNSVFECIVDSTQL
TSLKLELTSLIDEEKDSLRIYRLGNNYKTKVEHIGAKPSIDLEDPLIF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d3l PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Resolution3.49 Å
Binding residue
(original residue number in PDB)		Y7 V9 T11 S12 R33 N36 S37
Binding residue
(residue number reindexed from 1)		Y9 V11 T13 S14 R35 N38 S39
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8d3l, PDBe:8d3l, PDBj:8d3l
PDBsum8d3l
PubMed36272411
UniProtQ9KFX8|CAS2_HALH5 CRISPR-associated endonuclease Cas2 (Gene Name=cas2)

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