Structure of PDB 8cp4 Chain F Binding Site BS01

Receptor Information
>8cp4 Chain F (length=253) Species: 39152 (Methanococcus maripaludis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLLEKYNSLLEFFKNKKVIVAYSGGVDSTLISKIASDNAQTLAVTIDNGF
FSENVIKKAENRAKKYNIPQKTIKIDYLNEITSKDLENRCYNCKKRIAEE
LKRIKNELNYDIIVDGTIYDDIFEDRPGIKAFNESNIISPLSNLKFSKND
VFELSNYLKIDIPKKDTCMATRILSAPISKENMAKSNLAEEFIKLNFHIE
SYLRVRYLENIAIIELTKNESEKIFDNDSIERINTELKKIGFEKVVLDLN
FKG
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8cp4 Chain F Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cp4 Structure-based insights into the mechanism of [4Fe-4S]-dependent sulfur insertase LarE.
Resolution3.19 Å
Binding residue
(original residue number in PDB)		F56 C96 C99 K100 C174 T177
Binding residue
(residue number reindexed from 1)		F50 C90 C93 K94 C168 T171
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016783 sulfurtransferase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:8cp4, PDBe:8cp4, PDBj:8cp4
PDBsum8cp4
PubMed38100250
UniProtQ6LXV7

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