Structure of PDB 8bwf Chain F Binding Site BS01
Receptor Information
>8bwf Chain F (length=79) Species:
9606
(Homo sapiens) [
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GPPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTE
EAANTMVNYYTSVTPVLRGQPIYIQFSNH
Ligand information
>8bwf Chain f (length=12) Species:
9606
(Homo sapiens) [
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NQKRAQKALQVN
Receptor-Ligand Complex Structure
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PDB
8bwf
Rationally designed stapled peptides allosterically inhibit PTBP1-RNA-binding.
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
E72 L80
Binding residue
(residue number reindexed from 1)
E18 L26
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
GO:0003723
RNA binding
View graph for
Molecular Function
External links
PDB
RCSB:8bwf
,
PDBe:8bwf
,
PDBj:8bwf
PDBsum
8bwf
PubMed
37564416
UniProt
P26599
|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (Gene Name=PTBP1)
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