Structure of PDB 7zai Chain F Binding Site BS01

Receptor Information
>7zai Chain F (length=229) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQEWKEYAKRVLDEWQPKTKLGMLVKEGQITDIHEIFRKGYQIKEPEIID
VLLPEVNARENQEILDIALTVRMTDSGRRVRFRVLAAVGNRDGYVGLGIG
HGREVGIAIRKAINYAKLNIIEIKRGCGSWECRCRRPHSVPFTVEGKEGS
VRVKLIPGPRGLGLVIGDVGKKILRLAGIQDVWSQTLGETRTTVNFAKAV
FNALYNTNKVVVTPEMIERYGIVVGRAMP
Ligand information
>7zai Chain 2 (length=1497) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggaggccacugcuauggggguccgacuaagcc
augcgagucaagggggcgucccuucugggacgccaccggcggacggcuca
guaacacgucgguaaccuacccucgggagggggauaaccccgggaaacug
gggcuaaucccccauaggccugggguacuggaagguccccaggccgaaag
ggagccguaaggcuccgcccgaggaugggccggcggccgauuagguaguu
ggugggguaacggcccaccaagccgaagaucgguacgggccgugagagcg
ggagcccggagauggacacugagacacggguccaggcccuacggggcgca
gcaggcgcgaaaccuccgcaaugcgggaaaccgcgacggggggaccccca
gugccgugccucuggcacggcuuuuccggaguguaaaaagcuccgggaau
aagggcugggcaaggccgguggcagccgccgcgguaauaccggcggcccg
agugguggccacuauuauugggccuaaagcggccguagccgggcccguaa
gucccuggcgaaaucccacggcucaaccguggggcucgcuggggauacug
cgggccuugggaccgggagaggccggggguacccccgggguaggggugaa
auccuauaaucccggggggaccgccaguggcgaaggcgcccggcuggaac
ggguccgacggugagggccgaaggccaggggagcgaaccggauuagauac
ccggguaguccuggcuguaaaggaugcgggcuaggugucgggcgagcuuc
gagcucgcccggugccguagggaagccguuaagcccgccgccuggggagu
acggccgcaaggcugaaacuuaaaggaauuggcgggggagcacuacaagg
gguggagcgugcgguuuaauuggauucaacgccgggaaccucaccggggg
cgacggcaggaugaaggccaggcugaaggucuugccggacgcgccgagag
gaggugcauggccgccgucagcucguaccgugaggcguccacuuaagugu
gguaacgagcgagacccgcgcccccaguugccagucccucccgcucggga
gggaggcacucuggggggacugccggcgauaagccggaggaaggggcggg
cgacgguaggucaguaugccccgaaacccccgggcuacacgcgcgcuaca
augggcgggacaaugggugccgaccccgaaagggggagguaauccccuaa
acccgcccucaguucggaucgcgggcugcaacucgcccgcgugaagcugg
aaucccuaguacccgcgcgucaucaucgcgcggcgaauacgucccugcuc
cuugcacacaccgcccgucacuccacccgagcggggccuaggugaggccc
gaucuccuucgggaggucgggucgagccuaggcuccgugaggggggagaa
gucguaacaagguagccguaggggaaccuacggcucgaucaccuccu
...<<<<<.[.((((>>>>>.<<<<<<<<<..<<<<<<.<<......<<<
.<<<..<<<..<<.<<<<<<<<....>>>>>>>>.>>>>>......<<..
......<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<<....>>>
>>>.....>>>>>...<<<<<<<<<.<<......>>>>>>>>>>>.....
<<<<<<....>>>>>>.>>>>>>>..>>>>>>>>>.<<<....<<<..<<
<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>
>...>>>>.>>.<<<<<............>>>>>.<<<<....>>>>...
>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>>>>>>
..<<<<<<<<...>>>>>>>>...<<<<<<<<.......>>>>>>>>...
..<<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>.
.>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<
<<<<<<<<<....<<<<<<<<.....>>>>>>>>...>>>>>>>>..>>>
>>>>>>...<<<<<<.....<<<<<<<<<..<<<<<<<<<..<<<.....
.>>>.....>>>>>>>>>..>>.......<<....>>.>>>>>>>....>
>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<.<.....>.
>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<...
..>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<....
..<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<.<<<
<<<..<<<<<<<<<<......<<........>>..........<<<<<<<
...<<<<........<<<.<<<.......>>>.>>>......>>>>...<
<.<<<..<<<<<<<<<....<<<<<<.<<....>>...<<<<......>>
>>..>>>>>>....<<<<<.<<<<<<<..<<<..<<<<<<<<....>>>>
>>>>>>>...>>>>>>>.....<<<<<.....>>>>>........>>>>>
....>>>.>>>...>>>>>>>>....>>>>>>>...>>.>>>>>>>>...
..<<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>....
.>>>>>>>......<....<<<<<<<........>>>>>>>....>....
.>>>>>>.....<<<<<<<.......>>>>>>>.......>>...>>>>>
>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<<..<<<<<
<<<<<<<....>>>>>>>>>>>>..>>>>>>>>>>>>>..>>>.>>>>..
>.>>...>.....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
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PDB7zai Role of aIF5B in archaeal translation initiation.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		T71 V72 R73 M74 D76 S77 R79 R82 R84 H102 K112 K148 E149 S151 R153 V166 K172 W184 S185 T187 T191 R192 T193 N196 K199
Binding residue
(residue number reindexed from 1)		T70 V71 R72 M73 D75 S76 R78 R81 R83 H101 K111 K147 E148 S150 R152 V165 K171 W183 S184 T186 T190 R191 T192 N195 K198
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7zai, PDBe:7zai, PDBj:7zai
PDBsum7zai
PubMed35694843
UniProtQ9V1V5|RS5_PYRAB Small ribosomal subunit protein uS5 (Gene Name=rps5)

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