Structure of PDB 7ykw Chain F Binding Site BS01

Receptor Information
>7ykw Chain F (length=37) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
Ligand information
>7ykw Chain C (length=27) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RLANFLVHSSNNFGAILSSTNVGSNTY
Receptor-Ligand Complex Structure
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PDB7ykw A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core
Resolution3.6 Å
Binding residue
(original residue number in PDB)
L12 N14 H18 S19 S20 I26 S28 T30
Binding residue
(residue number reindexed from 1)
L12 N14 H18 S19 S20 I26 S28 T30
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:7ykw, PDBe:7ykw, PDBj:7ykw
PDBsum7ykw
PubMed36567711
UniProtP10997|IAPP_HUMAN Islet amyloid polypeptide (Gene Name=IAPP)

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