Structure of PDB 7wn4 Chain F Binding Site BS01

Receptor Information
>7wn4 Chain F (length=475) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVR
HENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCQDRKWNCTDHVCDAT
CSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSH
PSVKCKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYIILLL
GKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEE
DPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSD
VFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGK
VVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACP
VQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNP
SDPEHCQICHCDVVNLTCEACQEPG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7wn4 Chain F Residue 1301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7wn4 Structural mechanism of VWF D'D3 dimer formation.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		D879 N998 D1000 I1002 N1005 D1006
Binding residue
(residue number reindexed from 1)		D113 N232 D234 I236 N239 D240
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7wn4, PDBe:7wn4, PDBj:7wn4
PDBsum7wn4
PubMed35169124
UniProtP04275|VWF_HUMAN von Willebrand factor (Gene Name=VWF)

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