Structure of PDB 7u5y Chain F Binding Site BS01

Receptor Information

>7u5y Chain F (length=221) Species: 208964 (Pseudomonas aeruginosa PAO1)

HMQPFAIAPSILSADFARLGEDVDKVLAAGADIVHFDVMDNHYVPNLTIG
PMVCSALRKYGVSAPIDVHLMVSPVDRIIGDFIEAGATYITFHPEASQHI
DRSLQLIRDGGCKAGLVFNPATPLEVLKYVMDKVDMVLLMSVNPGFQKFI
PGTLDKLREARALIDASGREIRLEIDGGVNVKNIREIAAAGADTFVAGSA
IFNAPDYAEVIRAMHAELAQA

Ligand information

• Ligand ID: ZN
• InChI: InChI=1S/Zn/q+2
• InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Zn++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Zn+2]
• Formula: Zn
• Name: ZINC ION
• ChEMBL: CHEMBL1236970
• DrugBank: DB14532
• PDB chain: 7u5y Chain F Residue 300

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7u5y Crystal structure of ribulose-phosphate 3-epimerase from Pseudomonas aeruginosa
• Resolution: 2.55 Å
• Binding residue (original residue number in PDB): H34 D36 H68
• Binding residue (residue number reindexed from 1): H35 D37 H69
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 5.1.3.1: ribulose-phosphate 3-epimerase.

Gene Ontology

Molecular Function

• GO:0004750 D-ribulose-phosphate 3-epimerase activity
• GO:0016853 isomerase activity
• GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process
• GO:0006098 pentose-phosphate shunt
• GO:0009052 pentose-phosphate shunt, non-oxidative branch
• GO:0019323 pentose catabolic process

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:7u5y, PDBe:7u5y, PDBj:7u5y
• PDBsum: 7u5y
• UniProt: Q9I5T1