Structure of PDB 7tve Chain F Binding Site BS01

Receptor Information
>7tve Chain F (length=270) Species: 580240 (Saccharomyces cerevisiae W303) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTEDLAVAKIVKENPVARKMVRYILSRGESQNSIITRNKLQSVIHEAARE
ENIAKPSFSKMFMDINAILYNVYGFELQGLPSKGHRAQKFILLNNVPHSK
NFDDFKILQSAHTYEELIVTGEYIGDDIASGTSNTLESKLSTDRDLVYKG
VLSVILCIVFFSKNNILHQELIKFLETFGIPSDGSKIAILNITIEDLIKS
LEKREYIVRLEEKSDTDGEVISYRIGRRTQAELGLESLEKLVQEIMGLEK
EQTKSLHDDIIKSIGDSYSI
Ligand information
Receptor-Ligand Complex Structure
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PDB7tve Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		Q52 H56 R119
Binding residue
(residue number reindexed from 1)		Q41 H45 R86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0019789 SUMO transferase activity
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0016925 protein sumoylation
GO:0032204 regulation of telomere maintenance
GO:0140588 chromatin looping
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030915 Smc5-Smc6 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tve, PDBe:7tve, PDBj:7tve
PDBsum7tve
PubMed35648833
UniProtQ05541|NSE3_YEAST Non-structural maintenance of chromosome element 3 (Gene Name=NSE3)

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