Structure of PDB 7snq Chain F Binding Site BS01

Receptor Information
>7snq Chain F (length=212) Species: 11678 (Human immunodeficiency virus type 1 BH10) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PIVQNLQGQMVHQCISPRTLNAWVKVVEEKAFSPEVIPMFSALSCGATPQ
DLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPPGQMREPRGSDIAGT
TSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGP
KEPFRDYVDRFYKTLRAEQSQEVKNAATETLLVQNANPDCKTILKALGPG
ATLEEMMTACQG
Ligand information
>7snq Chain M (length=14) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PVLFPGQPFGQPPL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7snq Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection.
Resolution2.81 Å
Binding residue
(original residue number in PDB)
Q179 T186
Binding residue
(residue number reindexed from 1)
Q171 T178
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:7snq, PDBe:7snq, PDBj:7snq
PDBsum7snq
PubMed36202818
UniProtP03366|POL_HV1B1 Gag-Pol polyprotein (Gene Name=gag-pol)

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