Structure of PDB 7s78 Chain F Binding Site BS01

Receptor Information
>7s78 Chain F (length=929) Species: 28285 (Human adenovirus 5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTVAPT
HDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTYFDI
RGVLDRGPTFKPYSGTAYNALAPKGAPNPCEWDEAATALEQQKTHVFGQA
PYSGINITKEGIQIGVEGQTPKYADKTFQPEPQIGESQWYETEINHAAGR
VLKKTTPMKPCYGSYAKPTNENGGQGILVKQQNGKLESQVEMQFFSTTEA
TAGNGDNLTPKVVLYSEDVDIETPDTHISYMPTIKEGNSRELMGQQSMPN
RPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQL
LLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLGGVIN
TETLTKVKPKTGQENGWEKDATEFSDKNEIRVGNNFAMEINLNANLWRNF
LYSNIALYLPDKLKYSPSNVKISDNPNTYDYMNKRVVAPGLVDCYINLGA
RWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNL
LLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYATFFPM
AHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIPSRNW
AAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTFKKVA
ITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLA
NYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVGILHQ
HNNSGFVGYLAPTMREGQAYPANFPYPLIGKTAVDSITQKKFLCDRTLWR
IPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYVLFEV
FDVVRVHRPHRGVIETVYLRTPFSAGNAT
Ligand information
>7s78 Chain Z (length=25) Species: 28285 (Human adenovirus 5) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
FASLAPRHGSRPFQDIGTSNMSGGA
Receptor-Ligand Complex Structure
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PDB7s78 Structure of a Cell Entry Defective Human Adenovirus Provides Insights into Precursor Proteins and Capsid Maturation.
Resolution3.72 Å
Binding residue
(original residue number in PDB)		D18 P47 T48 V49 P51 N643 Y645 R675 R871 E920
Binding residue
(residue number reindexed from 1)		D16 P45 T46 V47 P49 N622 Y624 R654 R850 E899
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus
Cellular Component
GO:0019028 viral capsid
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7s78, PDBe:7s78, PDBj:7s78
PDBsum7s78
PubMed34774568
UniProtP04133|CAPSH_ADE05 Hexon protein (Gene Name=L3)

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