Structure of PDB 7qir Chain F Binding Site BS01

Receptor Information
>7qir Chain F (length=131) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDV
VVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFS
QTVSAVCLPSASDDFAAGTTCVTTGWGLTRY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7qir Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		E20 S26 W27 P28 W29 Q116 A120 V121 C122
Binding residue
(residue number reindexed from 1)		E5 S11 W12 P13 W14 Q101 A105 V106 C107
Enzymatic activity
Enzyme Commision number 3.4.21.1: chymotrypsin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7qir, PDBe:7qir, PDBj:7qir
PDBsum7qir
PubMed35755190
UniProtP00766|CTRA_BOVIN Chymotrypsinogen A

[Back to BioLiP]