Structure of PDB 7qid Chain F Binding Site BS01

Receptor Information
>7qid Chain F (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>7qid Chain E (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB7qid Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain
Resolution5.0 Å
Binding residue
(original residue number in PDB)		F1 Q4 H5 L6 C7 L11 L15 C19 R22 G23 F24 F25
Binding residue
(residue number reindexed from 1)		F1 Q4 H5 L6 C7 L11 L15 C19 R22 G23 F24 F25
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:7qid, PDBe:7qid, PDBj:7qid
PDBsum7qid
PubMed31727777
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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