Structure of PDB 7pnw Chain F Binding Site BS01

Receptor Information
>7pnw Chain F (length=208) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRYAPEFREPLIDKEYYRKPVAELTEEEKYDQELKKTQFIKAAAATETSS
VFADPVISKFTNMMMKGGNKVLARSLMAQTLEAVKRKQFEKYRAASAEEQ
ATIERNPYRIFHEALKNCEPVIGLVPILKGGHFYQVPVPLADRRRRFLAM
KWMITECRENKPRRTLMPEKLSHELLEAFHNRGPVIKRKHNMHKMAEANR
ALAHYRWW
Ligand information
>7pnw Chain A (length=954) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaagguuugguccuggccuuauaauuaauuagagguaaaauuacacaugc
aaaccuccauagaccgguguaaaaucccuuaaacauuuacuuaaaauuua
aggagaggguaucaagcacauuaaaauagcuuaagacaccuugccuagcc
acacccccacgggacucagcagugauaaauauuaagcaauaaacgaaagu
uugacuaaguuauaccucuuaggguugguaaauuucgugccagccaccgc
ggucauacgauuaacccaaacuaauuaucuucggcguaaaacgugucaac
uauaaauaaauaaauagaauuaaaauccaacuuauaugugaaaauucauu
guuaggaccuaaacucaauaacgaaaguaauucuagucauuuauaauaca
cgacagcuaagacccaaacugggauuagauaccccacuaugcuuagccau
aaaccuaaauaauuaauuaacaaaacuauuugccagagaacuacuagcca
uagcuuaaaacucaaaggacuuggcgguacuuuauauccaucuagaggag
ccuguucuauaaucgauaaaccccgcucuaccucaccaucucuugcuaau
ucagccuauauaccgccaucuucagcaaacccuaaaaagguauuaaagua
agcaaaagaaucaaacauaaaaacguuaggucaagguguagccaaugaaa
ugggaagaaaugggcuacauuuucuuauaaaagaacauuacuauacccuu
uaugaaacuaaaggacuaaggaggauuuaguaguaaauuaagaauagaga
gcuuaauugaauugagcaaugaaguacgcacacaccgcccgucacccucc
ucaaauuaaauuaaacuuaacauaauuaauuucuagacauccguuuauga
gaggagauaagucguaacaagguaagcauacuggaaagugugcuuggaau
aauc
..((((..<<<<<<.)))).<<<<<<<.<..<<<<<<<<..<.<<<.<<<
..<......>......<<......<<<<<<<<<..<<<<..>>>>.>>>>
>>>.>>.<<<....<<...<<....>>..>>......>>>..<<...>>.
>>.<<<....>>>.....>>>>>>>.........<<....<<<<....>>
>>..>>...>>.>>>>>>...<<<<<<<<.....(((.....((.>>>))
.......)))..>>>>>..>.>>>>>>>....<<<((.....<<<<....
<<............<<<<<<....<<<<<<<....<<......>>.....
>>>.>>>..>..........<<....>>.>>>>>>......>>....>>>
>....<<<<<<...<<...<<<<.........>>>>...>>>>>>>>...
.......<<<<.<<.....))..>>.>>>>.>>>.<<<.......<<<..
..>>>.....>>>..>>>>>><<<<<.<<<<<<....<...<<<<<..<<
<<<<<<<<.....<<........>>..........<<<<.<<........
...<<.<<<..<<<<<<.......<<..<<<<<....>>>.......>>.
.>>......<<.....>>..........>>>...>>>>>>>>....>>.>
>>>..>>.>>>>>>>>.....<<<<<....>>>>>.....<<..<.<<<<
<<......>>>>>>..>.>>.....>>>>>.....<<<<<<<........
.>>>>>>>.......>....>>>>>>>>>.>>....<..<<.<...<<<<
<<..<.<<<<<....<<....<<.....>>....>>......>>>>>>..
>>>>>>....>.>>...>.....<<<<<<<<<....>>>>>>>>>.....
....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7pnw Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Resolution3.09 Å
Binding residue
(original residue number in PDB)
S35 R36 K93 N96 M99 G101 G102 K104 L106 L110 L162 G165 F167 R178 F181 K185 R192 K195 R197 R198 T199 L200 M201 W241 W242
Binding residue
(residue number reindexed from 1)
S1 R2 K59 N62 M65 G67 G68 K70 L72 L76 L128 G131 F133 R144 F147 K151 R158 K161 R163 R164 T165 L166 M167 W207 W208
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7pnw, PDBe:7pnw, PDBj:7pnw
PDBsum7pnw
PubMed35676484
UniProtQ80X85|RT07_MOUSE Small ribosomal subunit protein uS7m (Gene Name=Mrps7)

[Back to BioLiP]