Structure of PDB 7jil Chain F Binding Site BS01

Receptor Information

>7jil Chain F (length=176) Species: 986 (Flavobacterium johnsoniae)

SRIGKSPIVIPAGVTVEVKDGIITVKGKKGQLVQEFSDVNVTVEGDQVLV
ERSSDHKDHRAKHGLFRSLISNMVVGVSEGFTKELELVGVGYRAANQGNK
LDLALGYSHNIVLEIAPEVSLETISEAGANPIVKLTSFDKQLLGQVAAKI
RGFRKPEPYKGKGVKFVGEVLRRKAG

Ligand information

>7jil Chain 1 (length=2742)

aaauaagggcguauggggaaugccuaggcucucagaggcgaugaaggacg
ugauaagcugcgaaaagcugcggggacuggcacacacagauugauccgca
gauauccgaauggggcaacccgcuauauugaagauauagcacaccgauag
gugggcaaacccgcugaacugaaacaucuaaguaggcggaggagaagaaa
acaaaagugauuccguaaguaguggcgagcgaacgcggauuagcccaaac
cagugcuacggcagugcugggguuguaacaugcagaaccggaaguuacug
gaaagugacgccaaagagggugauagccccguauggguaauaaauguggu
auccugaguagggcgggacacgugaaacccugucugaauucggcgggacc
auccgcuaaggcuaaauacuccugagagaccgauagugaaccaguaccgu
gagggaaaggugaaaagaaccgugaauaacggagugaaauagauccugaa
accauacgcuuacaagcggucggagcccuuucguggggugacggcgugcc
uuuugcauaaugagccuacgaguuaacgcugcuggcaaggauaaguacuu
caguacggauccgcagcgaaagcgagucugaauagggcgcuuuagucagu
aguguuagacgcgaaaccgugugaucuacccaugggcagguugaagcugu
gguaacacacaguggaggaccgaaccgguugacguugaaaagucuucgga
ugaccuguggguaggggugaaaggccaaucaaacucggaaauagcucgua
cuccccgaaaugcauuuaggugcagcguuaguuauaaaguuauacagagg
uagagcuacugauuggaugcgggggcuucaccgcccaccaauuccugaca
aacuccgaaugcuguauaauguucacuaacagugagggcuugggugcuaa
gguccaaguccgagagggaaagaacccagaccaucagcuaagguccccaa
auauaugcuaaguugaaagaacgagguuugucugcccagacagcuaggau
guuggcuuggaagcagcccauuuaaagagcguaacagcucacuagucgag
cggacgagcauggauaauaaucgggcauaagcauauuaccgaagcuaugg
auuugcaaguuugcaagugguaggggagcauucuaacaggguugaagguu
uuucguaaggagggcuggacugguuagaaaagaaaauguaggcauaagua
acgauaaugcgggcgagaaacccgcacaccgaaaaacuaagguuuccaca
gcuaugcuaaucagcuguggguuagucugguccuaaggcgaacccgaaag
ggacagucgauggcuaacggguuaauauucccguacuacuaauuacugug
auggggugacggagugaugaaagcgccgcgaacugacggaauaguucguu
gaaguaccuagcuauagguccuguaguaaaaugcgcaggaacuggugaaa
uacgauaguacucggagucgacaaagagauagugcgccuaagggcuucca
agaaaaaccucuaaacuucagguaauuaguaccaguaccguaaaccgaca
cagguaguugaggagagaauccuaaggugcucgagauauucauggcuaag
gaauuaggcaaaauagaccuguaacuucgggagaaaggucgcccugagca
aucagggccgcagugaagagguccaggcgacuguuuaucaaaaacacagg
gcucugcaaaaucguaagaugaaguauagggccugacaccugcccggugc
uggaagguuaagaggagauguuaucuucggagaagcauugaauugaagcc
ccaguaaacggcggccguaacuauaacgguccuaagguagcgaaauuccu
ugucggguaaguuccgaccugcacgaaugguguaacgaucuggacacugu
cucagccaugagcucggugaaauuguaguaacggugaagaugccguuuac
ccgcagugggacgaaaagacccugugcaccuuuacuauagcuuaguacug
accuuggauaaauguuuaucugaggccuaaccucgcugcgggggacagug
cuugguggguaguuugacugggguggucgccuccaaaagaguaacggagg
cuucuaaagguucccucaguacgcuugguaaccgugcguagagugcaaug
gcauaagggagcuugacugagagacauacaggucgaucagguacgaaagu
agagcauagugauccggugguuccgcauggaagggccaucgcucaaagga
uaaaagguacgccggggauaacaggcugaucucccccaagaguucauauc
gacggggggguuuggcaccucgaugucggcucgucacauccuggggcugg
agaaggucccaaggguugggcuguucgcccauuaaagugguacgcgagcu
ggguucagaacgucgugagacaguucggucucuaucuacugcgggcguua
gaaauuugaguggaucugauucuaguacgagaggaccgaauuggacuaac
cucuaguguaucuguugucccgccaggggcaccgcagaguagcuacguug
ggaagggauaagcgcugaaagcauauaagcgcgaaacccaccacaagaug
agauuucuuuuaaggaucguggaagaugaccacguugauaggcuauagau
guaaaggcaguaaugucauagucgaguaguacuaauaauccg

......<<<<<<<<<<.....<<<..<<<<<<<<<<<<<......<<<<<
<.....((.>>>.....<<<<<<<..<<<)).....>>>.....>>>>>>
>...>>>....<<<....>>><<<<<<<.....>>>>>>>.<<<<....>
>>>.>>...<<<<<<.....<<....>>......>>>>>.>.........
<<....>>...<<<<<.....<<.....>>....>>>>>...<<<....<
<<<<<<<.....>>>>>>>>.......<.<<......<<<...<<<<<..
....>>>>>((......<<<.....))>>>...>>>.......>>.....
.>........<<<<<<<...........>>>>>>>......<<<<<..<<
<<>>>>>..>>>......>>.>>>>>>>.>>...............<<..
..>>....>>.........<<<<.....>>>>.............>....
.>>>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>>...<.
<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<<<.<.
..>>>>...>>>...<<....>>..<<<<.....>>>>......>>>>>>
>>>>>>>..<<.<...<<<.<<.....<<<<<<<<<..<<<....<<<<<
<......>>>>>>.....>>>...<<<...<<<........>>>..>>>.
...>>>>>>>>>...<<<.....>>>......>>.>>>......>.>>..
<<<<<<....<<<<<....>>>>><<<<<<<<......<<<<<<<<<...
..<<<....<<.<.<<<....<<<<.........>>.>>...>>>.>.>>
..>>.>.....>>>>>>>>>....>>>>>>.>>..<<<<<<<<<<.....
.>>>>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((...
..<<<<<<.....<<......<<..<<<<<<<<<<.......<<<<<.<<
<..<<<<.......>>>>>>>.......<<......>>...>>>>>...>
>>>>>>>>>.>>..........)))>>...>>>>>>.>>>...>>>>>>>
<<<<<<<<..>>>>>>>>....>>>>>>..<<<<<<<.<.......<<<<
<<<<....>>>>>>>>....>.>>>>>>>........>>>>>><......
<<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<
<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<....>
>>...>>>...>>...<<<<<........>>>>>))<<<<<<<<<<<<<.
..<<<<<...<<<<<.......<<<<.<<<<<<....[[....>>>>>>.
...<<<....<<<..<<.<<<<<<.<<.....>>>>>>>>.>>>>>....
>>>.......<<<...<<..>>...>>>.....>>>>......>>>>>..
......>>>>>...>>....>>>>>>>>>>>>>>>..>>.....<<....
..>>>>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<
.........<.....<<<<<....<<..>>.....>>>>><<<<<<<...
.>>>>>>>............<<<<<<<<<..<<<.........>>>..<<
<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<
<<<..<<<<..<<...<<<<<<.<<....>>..>>>>>>...>>..>>>>
>>>>>..>>>>><<<<<<.......>>>>>>........<..........
.<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>..>..
>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<
<<<<<<<.<<<.<<......<<<<.<<<<<<..<<<<<.<<<.<<<<<.<
.<<<<<<<<<<<..>>>>>>>>>>>.>...<<<<<<.>>>>>>....>>>
>>.>>>..>>>>>..<<<<.....>>>><<<<<<...........>>>>>
>..<<...<<<<<<<...<<<<<.........>>>>>.....<<...(((
>>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>
>.>>))).......<<<<<<<.<<..>>>>..>>>>>>>>>.........
....>>>>..>>>>>>.......<<<<.<.<<<<<<...<<.......>>
...>>>>>>...>>>>.>.......<<<<<.<.<<<<..<<<<<<<<<..
....>>>>>>..>>>.<<<<<.....>>>>>.....>>>>...>...>>>
.>>....<<<<<<<....>>>.>>>>....>>..>>>>>>>>>>>....<
<<<<<<...<<<<..<<<<<<<...............>>>>>>>.<<<<<
...<<<<...<<<<<<<<<<<.]].>>>>>>..>>>>>...>>>>.>>>>
>...<<<....<<<<<...........>>>>>....>>>.>>>>......
.>>>>>>>.....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<
.....<<<<....>>>>...>>>..>>>>>.>>>...>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7jil Structural basis of sequestration of the anti-Shine-Dalgarno sequence in the Bacteroidetes ribosome.
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): R3 I4 R61 A62 L66 S69 L70 N73 G107 S109 K141 Q142 Q146 Y160 K161 K175
• Binding residue (residue number reindexed from 1): R2 I3 R60 A61 L65 S68 L69 N72 G106 S108 K140 Q141 Q145 Y159 K160 K174

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7jil, PDBe:7jil, PDBj:7jil
• PDBsum: 7jil
• PubMed: 33330920
• UniProt: A0A1M5L807