Structure of PDB 7dcs Chain F Binding Site BS01

Receptor Information
>7dcs Chain F (length=93) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHN
NMASFVRQLNMYGFRKVVHDTEFQHPCFLRGQEQLLENIKRKV
Ligand information
Receptor-Ligand Complex Structure
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PDB7dcs Structures of heat shock factor trimers bound to DNA.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
F18 F61 K62 H63 S68 R71 Q72 Y76 R117
Binding residue
(residue number reindexed from 1)
F4 F47 K48 H49 S54 R57 Q58 Y62 R91
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:7dcs, PDBe:7dcs, PDBj:7dcs
PDBsum7dcs
PubMed34458700
UniProtQ00613|HSF1_HUMAN Heat shock factor protein 1 (Gene Name=HSF1)

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