Structure of PDB 7cux Chain F Binding Site BS01

Receptor Information
>7cux Chain F (length=296) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKAEI
ENKGYNYERHGVGLDVPPIFRSHLDKMQKENHFLIFVKSWNTEAGVPLAT
LCSNLYHRERTSTDVMDSQEALAFLKCRTQNVSAAALFDRKRLQYLEKLN
LPESTHVEFVMFSTDVSHCVKDRLPKCVSAFANTEGGYVFFGVHDETCQV
IGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKGA
LRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMME
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7cux Chain F Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7cux Crystal structure of human Schlafen 5 N'-terminal domain (SLFN5-N) involved in ssRNA cleaving and DNA binding
Resolution3.29477 Å
Binding residue
(original residue number in PDB)
H266 C268
Binding residue
(residue number reindexed from 1)
H228 C230
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7cux, PDBe:7cux, PDBj:7cux
PDBsum7cux
PubMed
UniProtQ08AF3|SLFN5_HUMAN Schlafen family member 5 (Gene Name=SLFN5)

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