Structure of PDB 7c7a Chain F Binding Site BS01

Receptor Information
>7c7a Chain F (length=157) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INGVYYNEISRDLDISSSTQCLRFLKETVIPSLANNGNNSTSIQYHGISK
NDNIKKSVNKLDKQINMADRSLGLQQVVCIFSYGPHIQKMLSILEIFKKG
YIKNNKKIYQWNKLTSFDIKREGRNELQEERLKVPILVTLVSDSEIIDLN
LHSFTKQ
Ligand information
>7c7a Chain A (length=330) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauccaugaccaaagaaucgucacaaaucgaagcuuacaaaauggaguaa
aauuuuguuuacucaguaauaugcuuuggguugaaagucucccaccaauu
cguaugcggaaaacguaaugagauuuaaaaaaauuguuuaaaucaacuca
uuaaggaggaugcccuuggguauucugcuucuugaccugguaccucuauu
gcaggguacugguguuuucuucgguacuggauuccguuuguauggaaucu
aaaccauaguuaugacgauugcucuuucccgugcuggaucgaguaaccca
auggagcuuacuauucuugguccauggauu
<<<<<<<<<<<<<<.<<<<<<<......<<<<<<..........<<<<<<
<......>>>>>>>........>>>>>>........[.((((.<<<....
.....<<<.....>>><<<<<..........................>>>
>><<<.<<<<<<<<....>>>>>>>>.>>>......<<<<<<<<<.....
...>>>>>>>>>..........>>>...<<<<<<<<......>>>>>>>>
.............>>>>>>><<<<..<<<......>>>..>>>>......
..)))).]...>....>>>>>>.>>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7c7a Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		T20 N52 I55 K61 K90 R132
Binding residue
(residue number reindexed from 1)		T19 N51 I54 K60 K89 R131
Enzymatic activity
Enzyme Commision number 3.1.26.5: ribonuclease P.
Gene Ontology
Molecular Function
GO:0000171 ribonuclease MRP activity
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004526 ribonuclease P activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0042134 rRNA primary transcript binding
Biological Process
GO:0000294 nuclear-transcribed mRNA catabolic process, RNase MRP-dependent
GO:0000460 maturation of 5.8S rRNA
GO:0001682 tRNA 5'-leader removal
GO:0006364 rRNA processing
GO:0008033 tRNA processing
GO:0034965 intronic box C/D snoRNA processing
Cellular Component
GO:0000172 ribonuclease MRP complex
GO:0005634 nucleus
GO:0005655 nucleolar ribonuclease P complex
GO:0005697 telomerase holoenzyme complex
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7c7a, PDBe:7c7a, PDBj:7c7a
PDBsum7c7a
PubMed32586950
UniProtP53218|POP6_YEAST Ribonucleases P/MRP protein subunit POP6 (Gene Name=POP6)

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