Structure of PDB 7b1w Chain F Binding Site BS01

Receptor Information

>7b1w Chain F (length=234) Species: 3055 (Chlamydomonas reinhardtii)

MVQATSRVDKCKKSDIIVSPSILSADFSRLGDEVRAIDQAGCDWVHIDVM
DGRFVPNITIGPLVVEALRPVTDKVLDVHLMIVEPELRIPDFAKAGADII
SVHAEQSSTIHLHRTLNMVKDLGCKAGVVLNPGTSLSTIEEVLDVVDLIL
IMSVNPGFGGQKFIESQVAKIRNLKRMCNEKGVNPWIEVDGGVTPENAYK
VIDAGANALVAGSAVFKAKSYRDAIHGIKVSKAP

Ligand information

• Ligand ID: ZN
• InChI: InChI=1S/Zn/q+2
• InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Zn++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Zn+2]
• Formula: Zn
• Name: ZINC ION
• ChEMBL: CHEMBL1236970
• DrugBank: DB14532
• PDB chain: 7b1w Chain F Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7b1w Crystal structure of plastidial ribulose epimerase RPE1 from the model alga Chlamydomonas reinhardtii
• Resolution: 1.935 Å
• Binding residue (original residue number in PDB): H72 D74 H105 D216
• Binding residue (residue number reindexed from 1): H46 D48 H79 D190
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 5.1.3.1: ribulose-phosphate 3-epimerase.

Gene Ontology

Molecular Function

• GO:0004750 D-ribulose-phosphate 3-epimerase activity
• GO:0016853 isomerase activity
• GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process
• GO:0006098 pentose-phosphate shunt
• GO:0009052 pentose-phosphate shunt, non-oxidative branch
• GO:0009409 response to cold
• GO:0009624 response to nematode

Cellular Component

• GO:0005829 cytosol
• GO:0010319 stromule

External links

• PDB: RCSB:7b1w, PDBe:7b1w, PDBj:7b1w
• PDBsum: 7b1w
• PubMed: 38134324
• UniProt: A8IKW6