Structure of PDB 6zga Chain F Binding Site BS01

Receptor Information
>6zga Chain F (length=785) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPMNQLYPIDLLTELPPPITDLTLPPPPLVIPPERMLVPSELSNASPDYI
RSTLNAVPKNSSLLKKSKLPFGLVIRPYQHLYDDIDPPPLNEDGLIVRCR
RCRSYMNPFVTFIEQGRRWRCNFCRLANDVPMQMDQSDPNDPKSRYDRNE
IKCAVMEYMAPKEYTLRQPPPATYCFLIDVSQSSIKSGLLATTINTLLQN
LDSIPNHDERTRISILCVDNAIHYFKIPLDSENNEESADQINMMDIADLE
EPFLPRPNSMVVSLKACRQNIETLLTKIPQIFQSNLITNFALGPALKSAY
HLIGGVGGKIIVVSGTLPNLGIGKLQRRNESGVVNTSKETAQLLSCQDSF
YKNFTIDCSKVQITVDLFLASEDYMDVASLSNLSRFTAGQTHFYPGFSGK
NPNDIVKFSTEFAKHISMDFCMETVMRARGSTGLRMSRFYGHFFNRSSDL
CAFSTMPRDQSYLFEVNVDESIMADYCYVQVAVLLSLNNSQRRIRIITLA
MPTTESLAEVYASADQLAIASFYNSKAVEKALNSSLDDARVLINKSVQDI
LATYKKEIVVSNTAGGAPLRLCANLRMFPLLMHSLTKHMAFRSGIVPSDH
RASALNNLESLPLKYLIKNIYPDVYSLHDMADEAGLPGTIVLPQPINATS
SLFERYGLYLIDNGNELFLWMGGDAVPALVFDVFGTQDIFDIPIGKQEIP
VVENSEFNQRVRNIINQLRNHDDVITYQSLYIVRGASLSEPVNHASAREV
ATLRLWASSTLVEDKILNNESYREFLQIMKARISK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6zga Chain F Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zga Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network.
Resolution4.6 Å
Binding residue
(original residue number in PDB)		C231 C253 C256
Binding residue
(residue number reindexed from 1)		C99 C121 C124
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000149 SNARE binding
GO:0005048 signal sequence binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0016236 macroautophagy
GO:0070863 positive regulation of protein exit from endoplasmic reticulum
GO:0090110 COPII-coated vesicle cargo loading
GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport
Cellular Component
GO:0000139 Golgi membrane
GO:0000329 fungal-type vacuole membrane
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0012507 ER to Golgi transport vesicle membrane
GO:0016020 membrane
GO:0030127 COPII vesicle coat
GO:0031410 cytoplasmic vesicle
GO:0070971 endoplasmic reticulum exit site

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zga, PDBe:6zga, PDBj:6zga
PDBsum6zga
PubMed33795673
UniProtP40482|SEC24_YEAST Protein transport protein SEC24 (Gene Name=SEC24)

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